The human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS)
pandemic remains a world-wide health issue despite tremendous advances in antiretroviral …

CC chemokine receptor type 5 (CCR5) serves as a co-receptor for Human
immunodeficiency virus (HIV), enabling the virus to enter human CD4 T cells and …

Human Immunodeficiency virus (HIV) affects 30.8 to 42.9 million people and remains one of
the top 10 causes of death worldwide. Although the use of antiretrovirals has improved the …

Antiretroviral chemotherapeutics traditionally target viral pathways of fusion, entry,
transcription, integration, and protease function. Host cell-intrinsic mechanisms have …

Although several studies have determined key differences in envelope motifs between TF
and chronic HIV-1, it is still not known what the overall glycosylation profile is that is selected …

RATIONALE: Our laboratories birthed the field of human immunodeficiency virus (HIV)
theranostics. The new field allows simultaneous detection (diagnostics) and treatment …

Avec près de 35 millions de personnes infectées à travers le monde et 60.000 au Canada,
le VIH reste un problème majeur de santé publique. Bien que la thérapie antirétrovirale ait …

Dendritic cells (DCs), macrophages as well as osteoclasts (OCs) are emerging as target
cells of HIV-1 involved in i) sexual transmission, ii) virus dissemination in different tissues …

Tuberculosis (TB) still remains a big threat today, being the leading cause of death by a
single infectious agent. The TB epidemic is fueled by HIV along with the increasing drug …

Despite advances in the treatment of HIV-1 a cure remains elusive. A significant barrier to
the eradication of the virus from an infected individual is a pool of cells infected with …