Oxidative stress is proposed as a regulatory element in ageing and various neurological
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …

Deep brain stimulation (DBS) has evolved considerably over the past 4 decades. Although it
has primarily been used to treat movement disorders such as Parkinson's disease, essential …

In our ongoing research to discover natural products with neuroprotective effects,
hyperoside (quercetin 3-O-galactoside) was isolated from Acer tegmentosum, which has …

This focus of our research is to investigate the protective effect of Baicalin on apoptosis and
mTOR/AKT/GSK-3β pathway in substantia nigra neurons in a rat model for Parkinson's …

The present study was undertaken to investigate the effects of carvacrol and treadmill
exercise on memory deficit, rotational behavior and oxidative stress biomarkers in a 6-OHDA …

Phthalates have been used in a wide variety of consumer goods. Their versatility as
plasticizers has translated into worldwide use in a vast array of consumer products. These …

Discovery studies in animals constitute a cornerstone of biomedical research, but suffer from
lack of generalizability to human populations. We propose that large-scale interrogation of …

Parkinson's disease (PD) is a complex neurodegenerative disorder. It is characterized by a
combination of motor and nonmotor symptoms that gradually appear as consequence of the …