Mitochondria play a critical role in maintaining cellular function by ATP production. They are
also a source of reactive oxygen species (ROS) and proapoptotic factors. The role of …

The plasticity of skeletal muscle, whether an increase in size, change in metabolism, or
alteration in structural properties, is in a continuous state of flux largely dependent upon …

Following an insult by both intrinsic and extrinsic pathways, complex cellular, and molecular
interactions determine a successful recovery or inadequate repair of damaged tissue. The …

Background Mutations in αB‐crystallin result in proteotoxic cardiomyopathy with desmin
mislocalization to protein aggregates. Intermittent fasting (IF) is a novel approach to activate …

Statins, which reduce LDL-cholesterol by inhibition of 3-hydroxy-3-methylglutaryl–coenzyme
A reductase, are among the most widely prescribed drugs. Skeletal myopathy is a known …

Mitochondria perform a central role in life and death of the eukaryotic cell. They are major
players in the generation of macroergic compounds and function as integrated signaling …

Vimentin (VIM) is an intermediate filament (nanofilament) protein expressed in multiple cell
types, including astrocytes. Mice with VIM mutations of serine sites phosphorylated during …

The ADAMTS9 rs4607103 C allele is one of the few gene variants proposed to increase the
risk of type 2 diabetes through an impairment of insulin sensitivity. We show that the variant …

Background The pathophysiology of obstruction and swallowing dysfunction in snores and
sleep apnea patients remains unclear. Neuropathy and to some extent myopathy have been …

Aedes aegypti is the most important and widespread vector of arboviruses, including
dengue and zika. Insect dispersal through the flight activity is a key parameter that …