Rational design of nanocarriers for intracellular protein delivery
Protein/antibody therapeutics have exhibited the advantages of high specificity and activity
even at an extremely low concentration compared to small molecule drugs. However, they …
even at an extremely low concentration compared to small molecule drugs. However, they …
Engineered polymeric materials for biological applications: Overcoming challenges of the bio–nano interface
JD Simpson, SA Smith, KJ Thurecht, G Such - Polymers, 2019 - mdpi.com
Nanomedicine has generated significant interest as an alternative to conventional cancer
therapy due to the ability for nanoparticles to tune cargo release. However, while …
therapy due to the ability for nanoparticles to tune cargo release. However, while …
Targeted subcellular protein delivery using cleavable cyclic cell-penetrating peptides
AFL Schneider, ALD Wallabregue, L Franz… - Bioconjugate …, 2019 - ACS Publications
The delivery of entire functional proteins into living cells is a long-sought goal in science.
Cyclic cell-penetrating peptides (cCPPs) have proven themselves to be potent delivery …
Cyclic cell-penetrating peptides (cCPPs) have proven themselves to be potent delivery …
Enhanced delivery of plasmid DNA to skeletal muscle cells using a DLC8-binding peptide and ASSLNIA-modified PAMAM dendrimer
SD Jativa, N Thapar, D Broyles, E Dikici… - Molecular …, 2019 - ACS Publications
Skeletal muscle is ideally suited and highly desirable as a target for therapeutic gene
delivery because of its abundance, high vascularization, and high levels of protein …
delivery because of its abundance, high vascularization, and high levels of protein …
[PDF][PDF] Gene activation and SUMO-derepression through HIPK1-mediated p300 phosphorylation
P Rijal - 2019 - duo.uio.no
The transcription factor c-Myb is a master regulator of proliferation and differentiation in the
hematopoietic system. Both SUMO conjugation and SUMO binding appear to control the …
hematopoietic system. Both SUMO conjugation and SUMO binding appear to control the …
Studies on the proneural factor Ascl1 in the context of mitotic bookmarking
DFLS Soares - 2019 - search.proquest.com
Vertebrate neurogenesis is to large extent regulated by bHLH proneural transcription factors
(TFs) such as Ascl1 (also known as Mash1). They function as master regulators of …
(TFs) such as Ascl1 (also known as Mash1). They function as master regulators of …
Fluorescent protein biosensor for detection of kinase activity
HT Kao - 2019 - Google Patents
WO2019136421A1 - Fluorescent protein biosensor for detection of kinase activity - Google
Patents WO2019136421A1 - Fluorescent protein biosensor for detection of kinase activity …
Patents WO2019136421A1 - Fluorescent protein biosensor for detection of kinase activity …