Home to a culturally heterogeneous population, India is also a melting pot of genetic
diversity. The population architecture characterized by multiple endogamous groups with …

Behind the euphoric narrative of India as an emerging world power lies a complex and
evolving relationship between science and religion. Evoking the rich mythology of …

During periods of reduced O2 supply, the most profound changes in gene expression are
mediated by hypoxia-inducible factor (HIF) transcription factors that play a key role in cellular …

Highland native Andeans have resided at altitude for millennia. They display high aerobic
capacity (VO2max) at altitude, which may be a reflection of genetic adaptation to hypoxia …

EGLN1 encodes the hypoxia‐inducible factor (HIF) pathway prolyl hydroxylase 2 (PHD2)
that serves as an oxygen‐sensitive regulator of HIF activity. The EGLN1 locus exhibits a …

Highly valued across the world by genetic counsellors, medical geneticists and other
healthcare professionals, Harper's Practical Genetic Counselling has established itself over …

Aims Hypoxia-inducible factor-1 alpha (HIF-1α) is a key transcription factor responsible for
the induction of genes that facilitate adaptation to hypoxia. To study HIF-1 signalling in the …

Ayurveda and contemporary science comprehends human body as model to understand
disease state from very different perspective hence their methodology to describe disease …

We are witnessing a paradigm shift from a reactive healthcare model to Predictive,
Preventive, Personalized, and Participatory medicine for a holistic and proactive …

Objectives Placental hypoxia is a hallmark of preeclampsia. SNP rs479200 in the EGLN1
gene is associated with reduced responsiveness to hypoxia. Whether this translates into an …