Niacin in the central nervous system: an update of biological aspects and clinical applications

V Gasperi, M Sibilano, I Savini, MV Catani - International journal of …, 2019 - mdpi.com
Niacin (also known as “vitamin B3” or “vitamin PP”) includes two vitamers (nicotinic acid and
nicotinamide) giving rise to the coenzymatic forms nicotinamide adenine dinucleotide (NAD) …

Tau-mediated disruption of the spliceosome triggers cryptic RNA splicing and neurodegeneration in Alzheimer's disease

YC Hsieh, C Guo, HK Yalamanchili, M Abreha… - Cell reports, 2019 - cell.com
In Alzheimer's disease (AD), spliceosomal proteins with critical roles in RNA processing
aberrantly aggregate and mislocalize to Tau neurofibrillary tangles. We test the hypothesis …

Low molecular weight chitosan (∼ 20 kDa) protects acrylamide induced oxidative stress in D. melanogaster by restoring dopamine and KIF5B levels

PP Kumar, HP KV - Carbohydrate polymers, 2019 - Elsevier
Acrylamide (AA) presence and formation are predominant in fried, baked and heat-
processed foods. Using Drosophila model, we have investigated the dietary AA-arbitrate …