Pathophysiological, molecular and therapeutic issues of nonalcoholic fatty liver disease: an overview
S Marchisello, A Di Pino, R Scicali, F Urbano… - International journal of …, 2019 - mdpi.com
Nonalcoholic Fatty Liver Disease (NAFLD) represents the leading cause of liver disease in
developed countries but its diffusion is currently also emerging in Asian countries, in South …
developed countries but its diffusion is currently also emerging in Asian countries, in South …
GutSelf: Interindividual variability in the processing of dietary compounds by the human gastrointestinal tract
Nutritional research is currently entering the field of personalized nutrition, to a large extent
driven by major technological breakthroughs in analytical sciences and biocomputing. An …
driven by major technological breakthroughs in analytical sciences and biocomputing. An …
Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis
K Sołtysik, Y Ohsaki, T Tatematsu, J Cheng… - Nature …, 2019 - nature.com
The origin and physiological significance of lipid droplets (LDs) in the nucleus is not clear.
Here we show that nuclear LDs in hepatocytes are derived from apolipoprotein B (ApoB) …
Here we show that nuclear LDs in hepatocytes are derived from apolipoprotein B (ApoB) …
[HTML][HTML] The atypical antipsychotic quetiapine induces hyperlipidemia by activating intestinal PXR signaling
Quetiapine, one of the most prescribed atypical antipsychotics, has been associated with
hyperlipidemia and an increased risk for cardiovascular disease in patients, but the …
hyperlipidemia and an increased risk for cardiovascular disease in patients, but the …
High fat diet modulates the protein content of nutrient transporters in the small intestine of mice: possible involvement of PKA and PKC activity
AHT Hijo, CP Coutinho, TC Alba-Loureiro, JSM Leite… - Heliyon, 2019 - cell.com
Aims Chronic high fat consumption has been shown to modulate nutrient transporter content
in the intestine of obese mice; however it is unclear if this regulation occurs before or after …
in the intestine of obese mice; however it is unclear if this regulation occurs before or after …
[HTML][HTML] Hepatocyte and stellate cell deletion of liver fatty acid binding protein reveals distinct roles in fibrogenic injury
EP Newberry, Y Xie, C Lodeiro, R Solis… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Liver fatty acid binding protein (L-Fabp) modulates lipid trafficking in enterocytes,
hepatocytes, and hepatic stellate cells (HSCs). We examined hepatocyte vs. HSC L-Fabp …
hepatocytes, and hepatic stellate cells (HSCs). We examined hepatocyte vs. HSC L-Fabp …
Duo in a mystical realm—Nuclear lipid droplets and the inner nuclear membrane
K Sołtysik, Y Ohsaki, T Fujimoto - Contact, 2019 - journals.sagepub.com
The lipid droplet (LD) is a cytoplasmic organelle, but it also exists in the nucleus under some
conditions or in some cell types. New studies have revealed that nuclear LDs do not occur …
conditions or in some cell types. New studies have revealed that nuclear LDs do not occur …
[HTML][HTML] Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia
M Klevstig, M Arif, M Mannila, S Svedlund… - Journal of Molecular and …, 2019 - Elsevier
Aims The microsomal triglyceride transport protein (MTTP) is critical for assembly and
secretion of apolipoprotein B (apoB)-containing lipoproteins and is most abundant in the …
secretion of apolipoprotein B (apoB)-containing lipoproteins and is most abundant in the …
Removal of DHT can relieve polycystic ovarian but not metabolic abnormalities in DHT-induced hyperandrogenism in mice
LF Sun, YL Yang, TX Xiao, MX Li… - Reproduction, Fertility …, 2019 - CSIRO Publishing
Polycystic ovary syndrome (PCOS) is an endocrine disorder with a high prevalence in
women of childbearing age. To date, there is no method of efficiently diagnosing PCOS and …
women of childbearing age. To date, there is no method of efficiently diagnosing PCOS and …
Apolipoprotein (a) Secretion is Modulated by Sortilin, Proprotein Convertase Subtilisin/Kexin Type 9, and Microsomal Triglyceride Transfer Protein
J Clark - 2019 - search.proquest.com
Elevated plasma lipoprotein (a)(Lp (a)) levels are a causal risk factor for cardiovascular
disease (CVD), but development of specific Lp (a) lowering therapeutics has been hindered …
disease (CVD), but development of specific Lp (a) lowering therapeutics has been hindered …