Organoids-on-a-chip

SE Park, A Georgescu, D Huh - Science, 2019 - science.org
Recent studies have demonstrated an array of stem cell–derived, self-organizing miniature
organs, termed organoids, that replicate the key structural and functional characteristics of …

[HTML][HTML] Application of microfluidic chip technology in pharmaceutical analysis: A review

P Cui, S Wang - Journal of pharmaceutical analysis, 2019 - Elsevier
The development of pharmaceutical analytical methods represents one of the most
significant aspects of drug development. Recent advances in microfabrication and …

Measurement and analysis of cancer biomarkers based on electrochemical biosensors

F Cui, Z Zhou, HS Zhou - Journal of The Electrochemical Society, 2019 - iopscience.iop.org
Cancer is a dreadful disease with a high mortality rate, and it has become more and more
prevalent worldwide. Early diagnosis, prognosis and treatment monitoring with robust and …

[HTML][HTML] Cardiovascular disease models: a game changing paradigm in drug discovery and screening

H Savoji, MH Mohammadi, N Rafatian, MK Toroghi… - Biomaterials, 2019 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …

Engineering microfluidic organoid-on-a-chip platforms

F Yu, W Hunziker, D Choudhury - Micromachines, 2019 - mdpi.com
In vitro cell culture models are emerging as promising tools to understand human
development, disease progression, and provide reliable, rapid and cost-effective results for …

Organ‐on‐a‐chip for cancer and immune organs modeling

W Sun, Z Luo, J Lee, HJ Kim, KJ Lee… - Advanced …, 2019 - Wiley Online Library
Bridging the gap between findings in preclinical 2D cell culture models and in vivo tissue
cultures has been challenging; the simple microenvironment of 2D monolayer culture …

Microfluidic chip coupled with optical biosensors for simultaneous detection of multiple analytes: A review

Z Liao, Y Zhang, Y Li, Y Miao, S Gao, F Lin… - Biosensors and …, 2019 - Elsevier
This article reviews the recent advances in microfluidic-chip integrated optical biosensors for
simultaneous detection of multiple analytes. In particular, the principles and recent progress …

Flexible ferrofluids: Design and applications

X Zhang, L Sun, Y Yu, Y Zhao - Advanced Materials, 2019 - Wiley Online Library
Ferrofluids, also known as ferromagnetic particle suspensions, are materials with an
excellent magnetic response, which have attracted increasing interest in both industrial …

Microfluidics‐based biomaterials and biodevices

R Dong, Y Liu, L Mou, J Deng, X Jiang - Advanced Materials, 2019 - Wiley Online Library
The rapid development of microfluidics technology has promoted new innovations in
materials science, particularly by interacting with biological systems, based on precise …

Microfluidic bioprinting for organ-on-a-chip models

F Yu, D Choudhury - Drug discovery today, 2019 - Elsevier
Highlights•Bioprinting can be used to fabricate organ-on-a-chip models owing to its ability to
print multiple materials and cell types simultaneously with good spatial resolution and …