The what, where and how of delay activity

KK Sreenivasan, M D'Esposito - Nature reviews neuroscience, 2019 - nature.com
Working memory is characterized by neural activity that persists during the retention interval
of delay tasks. Despite the ubiquity of this delay activity across tasks, species and …

Glia-Neuron Interactions in Caenorhabditis elegans

A Singhvi, S Shaham - Annual review of neuroscience, 2019 - annualreviews.org
Glia are abundant components of animal nervous systems. Recognized 170 years ago,
concerted attempts to understand these cells began only recently. From these investigations …

[HTML][HTML] Glia accumulate evidence that actions are futile and suppress unsuccessful behavior

Y Mu, DV Bennett, M Rubinov, S Narayan, CT Yang… - Cell, 2019 - cell.com
When a behavior repeatedly fails to achieve its goal, animals often give up and become
passive, which can be strategic for preserving energy or regrouping between attempts. It is …

[HTML][HTML] Distinct mechanisms for visual and motor-related astrocyte responses in mouse visual cortex

M Slezak, S Kandler, PP Van Veldhoven… - Current Biology, 2019 - cell.com
Astrocytes are a major cell type in the mammalian nervous system, are in close proximity to
neurons, and show rich Ca 2+ activity thought to mediate cellular outputs. Astrocytes show …

Peripapillary and parafoveal vascular network assessment by optical coherence tomography angiography in aquaporin-4 antibody-positive neuromyelitis optica …

Y Huang, L Zhou, J ZhangBao, T Cai, B Wang… - British Journal of …, 2019 - bjo.bmj.com
Background/aims Current understanding of the alterations in the retinal vascular network in
neuromyelitis optica spectrum disorders (NMOSDs) is limited. We aim to assess the …

Selective deletion of glutamine synthetase in the mouse cerebral cortex induces glial dysfunction and vascular impairment that precede epilepsy and …

Y Zhou, R Dhaher, M Parent, QX Hu, B Hassel… - Neurochemistry …, 2019 - Elsevier
Glutamate-ammonia ligase (glutamine synthetase; Glul) is enriched in astrocytes and serves
as the primary enzyme for ammonia detoxification and glutamate inactivation in the brain …

The roles of astrocyte in the brain pathologies following ischemic stroke

L Sun, Y Zhang, E Liu, Q Ma, M Anatol, H Han, J Yan - Brain injury, 2019 - Taylor & Francis
Aim: In this work, we systematically explored the physiological functions of astrocytes and
their roles following ischemic stroke, additionally, the potential therapy strategy targeting the …

[HTML][HTML] Stores, channels, glue, and trees: active glial and active dendritic physiology

S Ashhad, R Narayanan - Molecular neurobiology, 2019 - Springer
Glial cells and neuronal dendrites were historically assumed to be passive structures that
play only supportive physiological roles, with no active contribution to information …

Astrocytic endfoot Ca2+ correlates with parenchymal vessel responses during 4-AP induced epilepsy: An in vivo two-photon lifetime microscopy study

C Zhang, M Tabatabaei, S Belanger… - Journal of Cerebral …, 2019 - journals.sagepub.com
Neurovascular coupling (NVC) underlying the local increase in blood flow during neural
activity forms the basis of functional brain imaging and is altered in epilepsy. Because …

[HTML][HTML] The impact of fasting on resting state brain networks in mice

T Tsurugizawa, B Djemai, A Zalesky - Scientific reports, 2019 - nature.com
Fasting is known to influence learning and memory in mice and alter the neural networks
that subserve these cognitive functions. We used high-resolution functional MRI to study the …