Congenital and perinatal infections represent major causes of permanent disability among
children worldwide. Linked together by the acronym TORCH, denoting Toxoplasma gondii …

Human parechovirus infections are the second most common cause of viral meningitis in
children. These infections are most frequently seen in infants younger than 90 days. Clinical …

Objectives This study aimed to prospectively collect detailed clinical information for all
enterovirus (EV) and human parechovirus (HPeV) meningitis cases in infants aged< 90 days …

Parechovirus A is a species in the Parechovirus genus within the Picornaviridae family that
can cause severe disease in children. Relatively little is known on Parechovirus A …

Magnetic resonance imaging (MRI) can provide detail of the soft tissues of the fetal and
neonatal brain that cannot be obtained by any other imaging modality. Conventional T1 and …

Background: Human parechovirus particularly genotype 3 (HPeV3) is an emerging infection
affecting predominantly young infants. The potential for neurologic sequelae in a vulnerable …

Experimental and clinical findings suggest a crucial role for inflammation in the onset of
pediatric seizures; this mechanism is not targeted by conventional antiepileptic drugs and …

Human parechovirus infection is an increasingly recognized cause of neonatal
meningoencephalitis. We describe characteristic clinical features and brain MR imaging …

ABSTRACT Human parechovirus 3 (HPeV3) infection is associated with sepsis
characterized by significant immune activation and subsequent tissue damage in neonates …

A total of 972 stool samples were collected from infants and children with acute
gastroenteritis (AGE) in pediatric clinics encompassing six localities (Hokkaido, Tokyo …