Personalized treatment is ideal for multiple sclerosis (MS) owing to the heterogeneity of
clinical features, but current knowledge gaps, including validation of biomarkers and …

Investigation of cerebrospinal fluid (CSF) in the diagnostic work-up in suspected multiple
sclerosis (MS) patients has regained attention in the latest version of the diagnostic criteria …

Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease with a complex
clinical course characterized by inflammation, demyelination, and axonal degeneration …

Background: In progressive multiple sclerosis (MS), glial activation is thought to be a
relevant mechanism of disability progression. Therefore, in vivo assessment of the glial cell …

Alzheimer's disease (AD) is the most common neurodegenerative disease and its diagnosis
has classically been based on clinical symptoms. Recently, a biological rather than a …

Background: Neurofilament light chain protein (NFL) and chitinase3-like1 (CHI3L1) have
gained importance recently as prognostic biomarkers in multiple sclerosis (MS). Objectives …

Background: Neurofilament light chain (NFL) and chitinase-3-like-1 (CHI3L1) concentrations
in cerebrospinal fluid (CSF) may have prognostic value in clinically isolated syndromes …

Recent progress in the research for underlying mechanisms in neurodegenerative diseases,
including Alzheimer disease (AD), Parkinson disease (PD), and amyotrophic lateral …

In demyelinating diseases including multiple sclerosis (MS), neural stem cells (NSCs) can
replace damaged oligodendrocytes if the local microenvironment supports the required …

Objective: Utilize immune cell profiles in the cerebrospinal fluid (CSF) to advance the
understanding and potentially support the diagnosis of inflammatory neuropathies. Methods …