Prion-like p53 amyloids in cancer

A Navalkar, S Ghosh, S Pandey, A Paul, D Datta… - Biochemistry, 2019 - ACS Publications
The global transcription factor, p53, is a master regulator of gene expression in cells.
Mutations in the TP53 gene promote unregulated cell growth through the inactivation of …

[HTML][HTML] Cancer stem cells in neuroblastoma therapy resistance

N Aravindan, D Jain, DB Somasundaram… - Cancer Drug …, 2019 - ncbi.nlm.nih.gov
Neuroblastoma (NB) is the most common cancer of infancy and accounts for nearly one
tenth of pediatric cancer deaths. This mortality rate has been attributed to the> 50 …

[HTML][HTML] Cytoplasmic restriction of mutated SOD1 impairs the DNA repair process in spinal cord neurons

J Li, M Song, S Moh, H Kim, DH Kim - Cells, 2019 - mdpi.com
Amyotrophic lateral sclerosis (ALS) caused by mutation of superoxide dismutase 1 (SOD1),
affects various cellular processes and results in the death of motor neurons with fatal …

Understanding the role of long non-coding RNAs in neuroblastoma development and progression

S Mitra - 2019 - gupea.ub.gu.se
Neuroblastoma (NB), a common cancer of childhood, contributes to 15% of all pediatric
cancer deaths. The improper neuronal differentiation of neural crest cells to mature neurons …

Unfavourable biological prognostic factors in Multiple Myeloma

U Painuly - 2019 - dspace.cuni.cz
Title I: Aurora kinase and FGFR3 inhibition results in significant apoptosis in molecular
subgroups of multiple myeloma In our pre-clinical study we examined the role of Aurora …

Clinico-Histopathological and Immunohistochemistry Study of Ruminant's Cutaneous Papillomavirus in Al-Muthanna Veterinary Hospital/Iraq

AH Al-Dabhawi, IA Erzuki, TAH Ali - 2019 - preprints.org
Background: Papillomaviruses (PVs) are double-stranded DNA viruses and are more
common in skin of ruminants in Iraq. A P53 (tumor suppressor protein) reveals an essential …

[引用][C] Crosstalk between the stress axes: Identification of the NIPA-p53 interaction

A Müller-Rudorf - 2019 - Dissertation, Universität Freiburg …