Kidney organoids: accurate models or fortunate accidents

MH Little, AN Combes - Genes & Development, 2019 - genesdev.cshlp.org
There are now many reports of human kidney organoids generated via the directed
differentiation of human pluripotent stem cells (PSCs) based on an existing understanding of …

Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk

AN Combes, B Phipson, KT Lawlor, A Dorison… - …, 2019 - journals.biologists.com
Recent advances in the generation of kidney organoids and the culture of primary nephron
progenitors from mouse and human have been based on knowledge of the molecular basis …

Generating kidney from stem cells

MH Little, LJ Hale, SE Howden… - Annual review of …, 2019 - annualreviews.org
Human kidney tissue can now be generated via the directed differentiation of human
pluripotent stem cells. This advance is anticipated to facilitate the modeling of human kidney …

[HTML][HTML] Comprehensive anatomic ontologies for lung development: A comparison of alveolar formation and maturation within mouse and human lung

H Pan, GH Deutsch, SE Wert… - Journal of biomedical …, 2019 - Springer
Background Although the mouse is widely used to model human lung development,
function, and disease, our understanding of the molecular mechanisms involved in …

[PDF][PDF] Correction: Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk (doi …

AN Combes, B Phipson, KT Lawlor, A Dorison… - …, 2019 - researchgate.net
Recent advances in the generation of kidney organoids and the culture of primary nephron
progenitors from mouse and human have been based on knowledge of the molecular basis …

In developing mouse kidneys, orientation of loop of Henle growth is adaptive and guided by long‐range cues from medullary collecting ducts

CH Chang, JA Davies - Journal of anatomy, 2019 - Wiley Online Library
The path taken by the loop of Henle, from renal cortex to medulla and back, is critical to the
ability of the kidney to concentrate urine and recover water. Unlike most developing tubules …

Ektopien der Niere, Harnwege und männlichen Geschlechtsorgane

G Mikuz - Der Pathologe, 2019 - Springer
The most frequent anomaly of the urogenital tract is a simple renal ectopia with one organ
lying in the pelvis. Crossed renal ectopia is a less common condition in which the ectopic …

[HTML][HTML] Induction of steady-state glomeruloid sphere by self-assembly from human embryonic kidney cells

H Abe, A Sakurai, A Ochi - Biochemical and biophysical research …, 2019 - Elsevier
The glomerulus is a network of capillaries known as a tuft, located at the beginning of a
nephron in the kidney. Here we describe a novel method for the induction of a …

Determining the Effect of R1 Peptide on lhx1a Dimerization

S Niraula - 2019 - search.proquest.com
Kidney disease is generally a secondary disease to other diseases like high blood pressure
and diabetes. Approximately 14.8% of American adults suffer from kidney disease where …

Exploring the Effects of the R1 Peptide on Zebrafish Development

TM Padmanabhan - 2019 - search.proquest.com
Abstract lhx1a is a transcriptional activator that plays many roles in zebrafish development. It
is expressed in the kidney and various tissues in the nervous system. Previously, we isolate …