Chemodynamic therapy: tumour microenvironment‐mediated Fenton and Fenton‐like reactions

Z Tang, Y Liu, M He, W Bu - Angewandte Chemie, 2019 - Wiley Online Library
Tailored to the specific tumour microenvironment, which involves acidity and the
overproduction of hydrogen peroxide, advanced nanotechnology has been introduced to …

Hydrogels as emerging materials for translational biomedicine

K Xue, X Wang, PW Yong, DJ Young… - Advanced …, 2019 - Wiley Online Library
Hydrogels have been extensively investigated as biomaterials because of their excellent
biocompatibility, and recent developments such as 3D printing and the incorporation of …

NIR-II light-modulated thermosensitive hydrogel for light-triggered cisplatin release and repeatable chemo-photothermal therapy

C Ruan, C Liu, H Hu, XL Guo, BP Jiang, H Liang… - Chemical …, 2019 - pubs.rsc.org
Cisplatin is one of the most effective chemotherapeutic agents, although its clinical use is
limited by severe nephrotoxicity. Multifunctional platform for spatiotemporally controlled …

Fluorescence imaging guided CpG nanoparticles-loaded IR820-hydrogel for synergistic photothermal immunotherapy

X Dong, J Liang, A Yang, Z Qian, D Kong, F Lv - Biomaterials, 2019 - Elsevier
As synergistic photothermal immunotherapy has developed as one of the most attractive
strategies for cancer therapy, it is crucial to design an effective photothermal immunotherapy …

An injectable thermosensitive photothermal-network hydrogel for near-infrared-triggered drug delivery and synergistic photothermal-chemotherapy

C Liu, X Guo, C Ruan, H Hu, BP Jiang, H Liang… - Acta biomaterialia, 2019 - Elsevier
Abstract Near-infrared (NIR)-responsive hydrogels have exhibited remarkable advantages
in biomedical applications especially for in situ therapeutic delivery, because of their deep …

Graphene-nanoparticle-based self-healing hydrogel in preventing postoperative recurrence of breast cancer

Q Li, J Wen, C Liu, Y Jia, Y Wu, Y Shan… - ACS Biomaterials …, 2019 - ACS Publications
Hydrogel is an ideal scaffold in the fields of regenerative medicine and tumor therapy
because of its biomimetic ability to modulate tissue microenvironment. Herein, we fabricated …

Engineered horseradish peroxidase-catalyzed hydrogels with high tissue adhesiveness for biomedical applications

TTH Thi, Y Lee, P Le Thi, KD Park - Journal of Industrial and Engineering …, 2019 - Elsevier
Adhesive hydrogels offer considerable potential in biomedical applications because of the
excellent integration between materials and tissues. Horseradish peroxidase (HRP) …

Enzyme-instructed self-assembly of a novel histone deacetylase inhibitor with enhanced selectivity and anticancer efficiency

Y Gao, C Zhang, J Chang, C Yang, J Liu, S Fan… - Biomaterials …, 2019 - pubs.rsc.org
Nowadays, how to improve the selectivity of chemotherapy drugs and reduce their side
effects is still a significant challenge for cancer research. Although enzyme-instructed self …

Multistage-targeted gold/mesoporous silica nanocomposite hydrogel as in situ injectable drug release system for chemophotothermal synergistic cancer therapy

J Zhou, M Wang, Y Han, J Lai… - ACS Applied Bio Materials, 2019 - ACS Publications
Injected tissue-affinity drug-laden nanocomposite hydrogels are promising materials for
tumor therapy owing to both maintenance and release of drug in situ. In this study, a …

Multifunctional chitosan/porous silicon@ Au nanocomposite hydrogels for long-term and repeatedly localized combinatorial therapy of cancer via a single injection

B Xia, W Zhang, H Tong, J Li, Z Chen… - … Biomaterials Science & …, 2019 - ACS Publications
Considering the future clinical applications of localized cancer therapy, it is of great
importance to construct injectable biodegradable nanocomposite hydrogels with …