[HTML][HTML] MRI T2 and T1ρ relaxation in patients at risk for knee osteoarthritis: a systematic review and meta-analysis

HF Atkinson, TB Birmingham, RF Moyer… - BMC musculoskeletal …, 2019 - Springer
Background Magnetic resonance imaging (MRI) T2 and T1ρ relaxation are increasingly
being proposed as imaging biomarkers potentially capable of detecting biochemical …

New advances in MRI diagnosis of degenerative osteoarthropathy of the peripheral joints

F Bruno, F Arrigoni, P Palumbo, R Natella… - La radiologia …, 2019 - Springer
Degenerative osteoarthropathy is one of the leading causes of the pain and disability from
musculoskeletal disease in the adult population. Magnetic resonance imaging (MRI) allows …

MRI T2 mapping of the knee providing synthetic morphologic images: comparison to conventional turbo spin-echo MRI

M Roux, T Hilbert, M Hussami, F Becce, T Kober… - Radiology, 2019 - pubs.rsna.org
Background Use of a T2 mapping sequence in addition to the conventional knee MRI
protocol increases sensitivity to early cartilage lesions but is time consuming. Purpose To …

[HTML][HTML] Towards patient-specific computational modelling of articular cartilage on the basis of advanced multiparametric MRI techniques

K Linka, A Schäfer, M Hillgärtner, M Itskov, M Knobe… - Scientific Reports, 2019 - nature.com
Cartilage degeneration is associated with tissue softening and represents the hallmark
change of osteoarthritis. Advanced quantitative Magnetic Resonance Imaging (qMRI) …

[HTML][HTML] Human articular cartilage mechanosensitivity is related to histological degeneration–a functional MRI study

S Nebelung, M Post, M Knobe, D Shah… - Osteoarthritis and …, 2019 - Elsevier
Objective To investigate changes in response to sequential pressure-controlled loading and
unloading in human articular cartilage of variable histological degeneration using serial T1ρ …

Degenerative changes in cartilage likely occur in the medial compartment after anterior cruciate ligament reconstruction

T Ushio, K Okazaki, K Osaki, Y Takayama… - Knee Surgery, Sports …, 2019 - Springer
Purpose Magnetic resonance imaging with T1ρ mapping is used to quantify the amount of
glycosaminoglycan in articular cartilage, which reflects early degenerative changes. The …

Biexponential T relaxation mapping of human knee menisci

R Baboli, A Sharafi, G Chang… - Journal of Magnetic …, 2019 - Wiley Online Library
Background Measuring T1ρ in the knee menisci can potentially be used as noninvasive
biomarkers in detecting early‐stage osteoarthritis (OA). Purpose To demonstrate the …

[HTML][HTML] Defective WNT signaling may protect from articular cartilage deterioration–a quantitative MRI study on subjects with a heterozygous WNT1 mutation

S Lehtovirta, RE Mäkitie, V Casula, M Haapea… - Osteoarthritis and …, 2019 - Elsevier
Objective WNT signaling is of key importance in chondrogenesis and defective WNT
signaling may contribute to the pathogenesis of osteoarthritis and other cartilage diseases …

[HTML][HTML] Through-thickness patterns of shear strain evolve in early osteoarthritis

F Maier, CG Lewis, DM Pierce - Osteoarthritis and Cartilage, 2019 - Elsevier
Objective Given the structural changes associated with the progression of Osteoarthritis
(OA), we hypothesized that patterns of through-thickness, large-strain shear evolve with …

Future Aspects of Clinical Osteoarthritis Therapies in the Continuum of Translational Research

S Schrenker, L Gao, M Cucchiarini… - … für Orthopädie und …, 2019 - thieme-connect.com
Die Arthrose betrifft eine signifikante Anzahl der erwachsenen Weltbevölkerung. Da in den
letzten Jahren verschiedene kausale Ansätze zur klinischen Arthrosetherapie auf der Basis …