A structure-informed atlas of human-virus interactions
G Lasso, SV Mayer, ER Winkelmann, T Chu, O Elliot… - Cell, 2019 - cell.com
While knowledge of protein-protein interactions (PPIs) is critical for understanding virus-host
relationships, limitations on the scalability of high-throughput methods have hampered their …
relationships, limitations on the scalability of high-throughput methods have hampered their …
Evolution of efficacious pangenotypic hepatitis C virus therapies
Hepatitis C compromises the quality of life of more than 350 million individuals worldwide.
Over the last decade, therapeutic regimens for treating hepatitis C virus (HCV) infections …
Over the last decade, therapeutic regimens for treating hepatitis C virus (HCV) infections …
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells
BA Fujimoto, M Young, L Carter… - American Journal …, 2019 - journals.physiology.org
Skeletal muscle handles~ 80–90% of the insulin-induced glucose uptake. In skeletal
muscle, insulin binding to its cell surface receptor triggers redistribution of intracellular …
muscle, insulin binding to its cell surface receptor triggers redistribution of intracellular …
Construction and analysis of a comprehensive protein interaction network of HCV with its host Homo sapiens
Abstract Background Hepatitis C Virus is becoming a major health problem in Asia and
across the globe since it is causing serious liver diseases including liver cirrhosis, chronic …
across the globe since it is causing serious liver diseases including liver cirrhosis, chronic …
A dual controllability analysis of influenza virus-host protein-protein interaction networks for antiviral drug target discovery
Background Host factors of influenza virus replication are often found in key topological
positions within protein-protein interaction networks. This work explores how protein states …
positions within protein-protein interaction networks. This work explores how protein states …
Inhibition of Hepatitis C Replication by Targeting the Molecular Chaperone Hsp90: Synthesis and Biological Evaluation of 4,5,6,7‐Tetrahydrobenzo[1,2‐d]thiazole …
Cellular chaperones that belong to the heat‐shock protein 90 (Hsp90) family are a
prerequisite for successful viral propagation for most viruses. The hepatitis C virus (HCV) …
prerequisite for successful viral propagation for most viruses. The hepatitis C virus (HCV) …
Integrating Virology and Proteomics to Comprehend Mechanisms of Innate Immune Signaling During Herpesvirus Infection
KKY Lum - 2019 - search.proquest.com
The mammalian immune system is equipped with an impressive array of intrinsic and innate
components that serve to clear pathogen infections by recognizing pathogen-associated …
components that serve to clear pathogen infections by recognizing pathogen-associated …
Characterization of functional determinants in the C-terminal part of hepatitis C virus E1 glycoprotein ectodomain
R Moustafa - 2019 - theses.hal.science
Hepatitis C virus is currently estimated to infect around 71 million people around the world.
However, recent advances in drug development led to the generation of pangenotypic direct …
However, recent advances in drug development led to the generation of pangenotypic direct …
[HTML][HTML] Caractérisation de déterminants fonctionnels dans la partie C-terminale de l'ectodomaine de la glycoprotéine E1 du virus de l'hépatite C
R Moustafa - 2019 - lilloa.univ-lille.fr
Aujourd'hui, le Virus de l'Hépatite C (VHC) infecte plus 70 millions de personnes dans le
monde. L'Organisation mondiale de la santé prévoit l'élimination du virus VHC d'ici 2030 …
monde. L'Organisation mondiale de la santé prévoit l'élimination du virus VHC d'ici 2030 …