Stroke is classified into two main groups depending on its aetiology; ischaemic stroke and
haemorrhagic stroke which successively develop from the occlusion or rupture of an artery …

Endothelial progenitors are a population of cells with the inherent capacity to differentiate
into mature endothelial cells and proangiogenic paracrine action. These characteristics …

Rationale: There is incomplete knowledge of the impact of bone marrow cells on the gut
microbiome and gut barrier function. Objective: We postulated that diabetes mellitus and …

Cell therapy is a progressively growing field that is rapidly moving from preclinical model
development to clinical application. Outcomes obtained from clinical trials reveal the …

Peroxiredoxins (Prdx) are a ubiquitous family of highly conserved antioxidant enzymes with
a cysteine residue that participate in the reduction of peroxides. This family comprises …

High glucose (HG) impairs endothelial progenitor cell (EPC) function. The activation of p38
mitogen‑activated protein kinase and the inhibition of the Akt/eNOS/NO pathway serve …

Objectives Individuals delivered from preeclamptic pregnancies exhibit a long-term
increased risk of developing cardiovascular and metabolic diseases, likely caused by …

Abstract CD34+ cells expressing KDR (CD34+/KDR+) represent a small proportion of
circulating progenitor cells that have the capacity to interact with platelets and to differentiate …

Background There is clinical need for a laboratory biomarker to identify patients who,
following an unprovoked venous thrombosis (VTE), are at low VTE recurrence risk and can …

Objective Circulating endothelial progenitor cells (EPCs) are regulated by stromal cell-
derived factor-1alpha (SDF-1α) and are reduced in type 2 diabetes mellitus (DM). SDF-1α is …