Adaptation by naïve CD4+ T cells to self-antigen–dependent TCR signaling induces functional heterogeneity and tolerance
WM Zinzow-Kramer, A Weiss… - Proceedings of the …, 2019 - National Acad Sciences
Naïve CD4+ T cells experience weak T cell receptor (TCR) signals induced by self-peptides
presented by MHC II. To investigate how these “basal” TCR signals influence responses to …
presented by MHC II. To investigate how these “basal” TCR signals influence responses to …
[HTML][HTML] Immunological paradigms, mechanisms, and models: conceptual understanding is a prerequisite to effective modeling
Z Grossman - Frontiers in immunology, 2019 - frontiersin.org
Most mathematical models that describe the individual or collective actions of cells aim at
creating faithful representations of limited sets of data in a self-consistent manner …
creating faithful representations of limited sets of data in a self-consistent manner …