In recent years, the worldwide spread of the so-called high-risk clones of multidrug-resistant
or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa has become a public …

ABSTRACT In June 2017, the National Institute of Allergy and Infectious Diseases, part of
the National Institutes of Health, organized a workshop entitled “Pharmacokinetics …

Background: Morbidity and mortality due to multidrug-resistant (MDR) bacteria are of great
concern in burn patients. In this critical condition, synergism between antimicrobial peptides …

Objectives Ceftolozane/tazobactam is a potential tool for infections caused by multidrug-
resistant (MDR) Pseudomonas aeruginosa (P. aeruginosa), but its efficacy against some …

Combinations of antimicrobial agents are often used in the management of infectious
diseases. Antimicrobial agents used as part of combination therapy are often selected …

Background Extensively drug-resistant (XDR) Pseudomonas aeruginosa (P. aeruginosa)
and particularly P. aeruginosa high-risk clones, are of growing concern because treatment …

Renal transplantation is a vital treatment option in children with ESRD with more than
10,000 pediatric kidney transplants and survival rates of greater than 80% at 10 years post …

Due to lack of better therapeutic options, colistin use for extensively drug-resistant Gram-
negative organisms was revived in the past two decades, including in patients in intensive …

In the last decade, considerable advancements have been made to identify the
pharmacokinetic/pharmacodynamic (PK/PD) index that defines the antimicrobial activity of …

We compared the efficacies of meropenem alone and in combination with colistin against
two strains of extended-spectrum-β-lactamase-producing Klebsiella pneumoniae, using an …