Nanoparticle-based drug delivery in the inner ear: current challenges, limitations and opportunities

R Mittal, SA Pena, A Zhu, N Eshraghi… - Artificial cells …, 2019 - Taylor & Francis
Hearing loss is the most common neurosensory impairment worldwide. While conductive
hearing loss can be managed by surgery, the management of sensorineural hearing loss …

Local drug delivery for prevention of hearing loss

LP Rybak, A Dhukhwa, D Mukherjea… - Frontiers in Cellular …, 2019 - frontiersin.org
Systemic delivery of therapeutics for targeting the cochlea to prevent or treat hearing loss is
challenging. Systemic drugs have to cross the blood-labyrinth barrier (BLB). BLB can …

Solid lipid nanoparticles loaded with glucocorticoids protect auditory cells from cisplatin-induced ototoxicity

B Cervantes, L Arana, S Murillo-Cuesta… - Journal of clinical …, 2019 - mdpi.com
Cisplatin is a chemotherapeutic agent that causes the irreversible death of auditory sensory
cells, leading to hearing loss. Local administration of cytoprotective drugs is a potentially …

Anti-inflammatory surface coatings based on polyelectrolyte multilayers of heparin and polycationic nanoparticles of naproxen-bearing polymeric drugs

H Al-Khoury, E Espinosa-Cano, MR Aguilar… - …, 2019 - ACS Publications
Immune response to biomaterials can produce chronic inflammation and fibrosis leading to
implant failure, which is related to the surface properties of the biomaterials. This work …

Has vitamin E any shreds of evidence in cisplatin‐induced toxicity

B Hakiminia, A Goudarzi… - Journal of Biochemical …, 2019 - Wiley Online Library
Cisplatin is one of the highly consumed and effective antitumor agents whose clinical
application is accompanied by nephrotoxicity adverse reaction. Also, other complications …

Opportunities and challenging issues of nanomaterials in otological fields: An occupational health perspective

V Leso, L Fontana, ML Ercolano, R Romano… - Nanomedicine, 2019 - Taylor & Francis
Nanotechnology may offer innovative solutions to overcome the physiological and
anatomical barriers that make the diagnosis and treatment of ear diseases an extremely …

Potential use of polymeric particles for the regulation of plant growth

AES Pereira, BT Sousa, MJ Iglesias, VA Alvarez… - Polymers for agri-food …, 2019 - Springer
Plant growth regulators (PGRs) are molecules widely applied in the agriculture, leading to
increased crop yield and improved quality of agricultural products. These compounds act as …

for the Regulation of Plant Growth

AES Pereira, BT Sousa, MJ Iglesias… - Polymers for Agri …, 2019 - books.google.com
Plant growth regulators (PGRs) are molecules widely applied in the agriculture, leading to
increased crop yield and improved quality of agricultural products. These compounds act as …