Nowadays, mesenchymal stem cells (MSCs) are essential players in cellular therapy and
regenerative medicine. MSCs are used to treat cardiac disorders by intramyocardial …

Ischemia reperfusion (IR) injury is a process defined by the temporary loss of blood flow and
tissue perfusion followed later by restoration of the same. Brief periods of IR can be tolerated …

Simple Summary The heart and lung play an essential role in physiological homeostasis,
especially in a hypoxic environment. The effect of aging on HIF-1α, HIF-2α, HIF-3α and …

Cardiac c-kit cells show promise in regenerating an injured heart. While heart disease
commonly affects elderly patients, it is unclear if autologous cardiac c-kit cells are …

Mesenchymal stem cells (MSCs) are known to secrete cardioprotective paracrine factors that
can potentially activate endogenous cardiac c-kit cells (CCs). This study aims to optimise …

G01N33/5008—Chemical analysis of biological material, eg blood, urine; Testing involving
biospecific ligand binding methods; Immunological testing involving human or animal cells …

Mitochondria play a crucial role in regulation of rhythmical contraction of myocardium,
myocardiocyte physiology, stress response and redox signaling cascades, and overall heart …

Regenerative medicine deals with the restoration of damaged or injured tissues in patients
suffering from catastrophic injuries or chronic diseases in which their own body's …

Cardiovascular disease continues to be the leading cause of death in New Zealand and
throughout the world. Apart from orthotopic heart transplantation, no current treatment can …

Heart disease is the main cause of mortality worldwide. The available treatments are limited,
high risk and often inefficient. Cell-based therapies are being developed to provide an …