The autonomic nervous system and cardiac arrhythmias: current concepts and emerging therapies
Research into cardiac autonomic control has received great interest in the past 20 years,
and we are now at a critical juncture with regard to the clinical translation of the experimental …
and we are now at a critical juncture with regard to the clinical translation of the experimental …
Electroceutical targeting of the autonomic nervous system
Autonomic nerves are attractive targets for medical therapies using electroceutical devices
because of the potential for selective control and few side effects. These devices use novel …
because of the potential for selective control and few side effects. These devices use novel …
[HTML][HTML] Head rules over the heart: cardiac manifestations of cerebral disorders
AP Hrishi, KR Lionel, U Prathapadas - Indian journal of critical care …, 2019 - ncbi.nlm.nih.gov
ABSTRACT The Brain-Heart interaction is becoming increasingly important as the
underlying pathophysiological mechanisms become better understood.“Neurocardiology” is …
underlying pathophysiological mechanisms become better understood.“Neurocardiology” is …
Neuromodulation for ventricular tachycardia and atrial fibrillation: a clinical scenario-based review
Autonomic dysregulation in cardiovascular disease plays a major role in the pathogenesis of
arrhythmias. Cardiac neural control relies on complex feedback loops consisting of efferent …
arrhythmias. Cardiac neural control relies on complex feedback loops consisting of efferent …
Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation
C Jungen, K Scherschel, F Flenner… - American Journal …, 2019 - journals.physiology.org
Patients with type 2 diabetes mellitus (T2DM) have a greater risk of developing life-
threatening cardiac arrhythmias. Because the underlying mechanisms and potential …
threatening cardiac arrhythmias. Because the underlying mechanisms and potential …
New approaches in the management of sudden cardiac death in patients with heart failure—targeting the sympathetic nervous system
MG Kiuchi, JM Nolde, H Villacorta… - International Journal of …, 2019 - mdpi.com
Cardiovascular diseases (CVDs) have been considered the most predominant cause of
death and one of the most critical public health issues worldwide. In the past two decades …
death and one of the most critical public health issues worldwide. In the past two decades …
[HTML][HTML] Cardiac sympathectomy and spinal cord stimulation attenuate reflex-mediated norepinephrine release during ischemia preventing ventricular fibrillation
JL Ardell, RD Foreman, JA Armour, K Shivkumar - JCI insight, 2019 - ncbi.nlm.nih.gov
The purpose of this study was to define the mechanism by which cardiac neuraxial
decentralization or spinal cord stimulation (SCS) reduces ischemia-induced ventricular …
decentralization or spinal cord stimulation (SCS) reduces ischemia-induced ventricular …
β-Adrenergic Receptor Stimulation and Alternans in the Border Zone of a Healed Infarct: An ex vivo Study and Computational Investigation of Arrhythmogenesis
Background: Following myocardial infarction (MI), the myocardium is prone to calcium-
driven alternans, which typically precedes ventricular tachycardia and fibrillation. MI is also …
driven alternans, which typically precedes ventricular tachycardia and fibrillation. MI is also …
Thoracic spinal cord neuromodulation obtunds dorsal root ganglion afferent neuronal transduction of the ischemic ventricle
S Salavatian, SM Ardell, M Hammer… - American Journal …, 2019 - journals.physiology.org
Aberrant afferent signaling drives adverse remodeling of the cardiac nervous system in
ischemic heart disease. The study objective was to determine whether thoracic spinal dorsal …
ischemic heart disease. The study objective was to determine whether thoracic spinal dorsal …
[HTML][HTML] Proarrhythmic proclivity of left-stellate ganglion stimulation in a canine model of drug-induced long-QT syndrome type 1
RMA Ter Bekke, AME Moers, MMJ de Jong… - International Journal of …, 2019 - Elsevier
Background Left-stellate ganglion stimulation (LSGS) can modify regional dispersion of
ventricular refractoriness, promote triggered activity, and reduce the threshold for ventricular …
ventricular refractoriness, promote triggered activity, and reduce the threshold for ventricular …