Methylation Dynamics of RASSF1A and Its Impact on Cancer

G Malpeli, G Innamorati, I Decimo, M Bencivenga… - Cancers, 2019 - mdpi.com
5-methyl cytosine (5mC) is a key epigenetic mark entwined with gene expression and the
specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for …

RASSF 1A controls tissue stiffness and cancer stem‐like cells in lung adenocarcinoma

D Pankova, Y Jiang, M Chatzifrangkeskou… - The EMBO …, 2019 - embopress.org
Lung cancer remains the leading cause of cancer‐related death due to poor treatment
responses and resistance arising from tumour heterogeneity. Here, we show that adverse …

Origins of DNA methylation defects in Wilms tumors

Z Anvar, B Acurzio, J Roma, F Cerrato, G Verde - Cancer letters, 2019 - Elsevier
Wilms tumor is an embryonic renal cancer that typically presents in early childhood and
accounts for 7% of all paediatric cancers. Different genetic alterations have been described …

MUC1-C represses the RASSF1A tumor suppressor in human carcinoma cells

H Rajabi, T Hata, W Li, MD Long, Q Hu, S Liu, D Raina… - Oncogene, 2019 - nature.com
RASSF1A encodes a tumor suppressor that inhibits the RAS→ RAF→ MEK→ ERK pathway
and is one of the most frequently inactivated genes in human cancers. MUC1-C is an …

Fluorescent regulators of RASSF1A expression and human cancer cell proliferation

ML Brown, KD Sheikh, MA Paige, P Banerjee… - US Patent …, 2019 - Google Patents
US10457639B2 - Fluorescent regulators of RASSF1A expression and human cancer cell
proliferation - Google Patents US10457639B2 - Fluorescent regulators of RASSF1A expression …

Biominerals formed by DNA and calcium oxalate or hydroxyapatite: a comparative study

G Revilla-López, AM Rodríguez-Rivero, LJ Del Valle… - Langmuir, 2019 - ACS Publications
Biominerals formed by DNA and calcium oxalate (CaOx) or hydroxyapatite (HAp), the most
important and stable phase of calcium phosphate) have been examined and compared …

Ras association domain family 1 isoform A suppresses colonic tumor cell growth through p21WAF1 activation in a p53‐dependent manner

SJ Oh, MG Lee, JR Moon, CK Lee… - Journal of …, 2019 - Wiley Online Library
Abstract Background and Aim Despite the frequent loss of Ras association domain family 1
isoform A (RASSF1A) expression in various cancers, the precise mechanism underlying its …

[PDF][PDF] The Role and Regulation of Semaphorin 3B in Breast Cancer Progression

N Shesha - 2019 - etheses.whiterose.ac.uk
Abstract Semaphorin 3B (SEMA3B) is an 83 kDa secreted protein of the semaphorin family
which has recently been shown to play an important role in angiogenesis and tumour …

Characterization of Chromosomal Abnormalities Reveals Non-Canonical Hippo Kinase Functions in Hematologic Malignancy

SA Stoner - 2019 - escholarship.org
Chromosomal abnormalities are frequent events in human cancer and are especially
prevalent in hematological malignancies. Here, through the characterization of …

Differential colorectal cancer genomics between east and west.

J Yu, JJY Sung - Journal of Gastroenterology & Hepatology, 2019 - search.ebscohost.com
Differential colorectal cancer genomics between east and west Page 1 EDITORIAL
Differential colorectal cancer genomics between east and west Colorectal cancer (CRC) is …