Background Dihydromyricetin (DMY) is an important plant flavonoid, which has received
great attention due to its health-benefiting activities, including antioxidant, antimicrobial, anti …

Enteric coating is a common procedure in the development of oral pharmaceutical dosage
forms. The main advantage of enteric coating is that it protects the drug from acidic pH and …

Objectives Co-ingestion of oral dosage forms with meals can cause substantial changes in
bioavailability relative to the fasted state. Food-mediated effects on bioavailability can have …

Bacterial β-glucuronidase (GUS) enzymes cause drug toxicity by reversing Phase II
glucuronidation in the gastrointestinal tract. While many human gut microbial GUS enzymes …

Background Of the various drug therapies that influence gastrointestinal (GI) physiology, one
of the most important are the acid-reducing agents (ARAs). Because changes in GI …

Physiologically based absorption modeling was conducted to predict bioequivalence (BE)
for immediate release (IR) and controlled release (CR) formulations. In case of the CR …

Objectives The main objective of the present work was to combine in-vitro and in-silico tools
to better understand the in-vivo behavior of the immediate release (IR) formulation of …

Among all the subclasses of flavonoids, anthocyanins (ACNs) are unique because they can
exhibit different colors while undergoing pH-dependent reversible transformations. ACNs …

Background and Objective SUBA-itraconazole and Sporanox are two oral formulations of
itraconazole. Drug–drug interactions with omeprazole have been previously reported; …

The influence of dietary flavonoids on human physiology and ageing is a subject of high
interest, involving consumers, food producers, the medical community, and the drug …