Inhibitory synapse formation at the axon initial segment

AJ Nathanson, PA Davies, SJ Moss - Frontiers in molecular …, 2019 - frontiersin.org
The axon initial segment (AIS) is the site of action potential (AP) initiation in most neurons
and is thus a critical site in the regulation of neuronal excitability. Normal function within the …

Identification of a core amino acid motif within the α subunit of GABAARs that promotes inhibitory synaptogenesis and resilience to seizures

AJ Nathanson, Y Zhang, JL Smalley, TA Ollerhead… - Cell reports, 2019 - cell.com
The fidelity of inhibitory neurotransmission is dependent on the accumulation of γ-
aminobutyric acid type A receptors (GABA A Rs) at the appropriate synaptic sites. Synaptic …

Voluntary wheel running exercise evoked by food-restriction stress exacerbates weight loss of adolescent female rats but also promotes resilience by enhancing …

TG Chowdhury, GS Wable, YW Chen… - Cerebral …, 2019 - academic.oup.com
Adolescence is marked by increased vulnerability to mental disorders and maladaptive
behaviors, including anorexia nervosa. Food-restriction (FR) stress evokes foraging, which …

An Amino Acid Motif Within the GABAA Receptor α2 Subunit Promotes Inhibitory Synaptogenesis and Seizure Resilience

AJ Nathanson - 2019 - search.proquest.com
The efficacy of inhibitory neurotransmission is dependent on the accumulation of specific
synaptic GABA A receptor (GABA AR) subtypes at the appropriate synaptic sites. To assess …

Signal Processing in the Brainstem Auditory Nuclei

H Ohmori, H Ohmori - Auditory Information Processing, 2019 - Springer
Neurons in ascending auditory nuclei are specialized to extract and process the sound
signals that are encoded as firing patterns of auditory nerve fibers (ANFs). Sound …

Method for quantitative assessment of acetabular bone defects

G Hettich, RA Schierjott… - Journal of …, 2019 - opus.bibliothek.uni-wuerzburg.de
Poor or variable oral bioavailability is of major concern regarding safety and efficacy for the
treatment of patients with poorly water-soluble drugs (PWSDs). The problem statement of …