Signaling natural products from human pathogenic bacteria

Z Hu, W Zhang - ACS infectious diseases, 2019 - ACS Publications
Natural products from microorganisms are important small molecules that play roles in
various biological processes like cellular growth, motility, nutrient acquisition, stress …

[HTML][HTML] Glucose regulates tissue-specific chondro-osteogenic differentiation of human cartilage endplate stem cells via O-GlcNAcylation of Sox9 and Runx2

C Sun, W Lan, B Li, R Zuo, H Xing, M Liu, J Li… - Stem Cell Research & …, 2019 - Springer
Background The degenerative disc disease (DDD) is a major cause of low back pain. The
physiological low-glucose microenvironment of the cartilage endplate (CEP) is disrupted in …

Cariogenic Streptococcus mutans produces strain-specific antibiotics that impair commensal colonization

X Tang, Y Kudo, J Baker, S LaBonte, PA Jordan… - bioRxiv, 2019 - biorxiv.org
Streptococcus mutans is a common constituent of dental plaque and an etiologic agent of
dental caries (tooth decay). Here we elucidate a biosynthetic pathway, encoded by globally …