[HTML][HTML] The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome

T Ried, GA Meijer, DJ Harrison, G Grech… - Molecular aspects of …, 2019 - Elsevier
Aneuploidy, the unbalanced state of the chromosome content, represents a hallmark of most
solid tumors, including colorectal cancer. Such aneuploidies result in tumor specific genomic …

[HTML][HTML] Trastuzumab specific epitope evaluation as a predictive and prognostic biomarker in gastric cancer patients

J Koh, SK Nam, YW Lee, JW Kim, KW Lee, CY Ock… - Biomolecules, 2019 - mdpi.com
While human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC)
antibodies bind to the intracellular domain, trastuzumab binds to the extracellular epitope of …

Successful desensitization of a patient with cetuximab hypersensitivity: A case report

M Solduzian, S Anvari… - Journal of Oncology …, 2019 - journals.sagepub.com
Background Severe hypersensitivity reaction is a dangerous adverse drug reaction in
patients receiving cetuximab. It requires drug discontinuation and medical management …

[HTML][HTML] Synthesis and evaluation of 64Cu-radiolabeled NOTA-cetuximab (64Cu-NOTA-C225) for immuno-PET imaging of EGFR expression

X Xu, T Liu, F Liu, X Guo, L Xia, Q Xie, N Li… - Chinese Journal of …, 2019 - ncbi.nlm.nih.gov
Objective Epidermal growth factor receptor (EGFR) is overexpressed in a wide variety of
solid tumors, serving as a well-characterized target for cancer imaging or therapy. In this …

结直肠癌抗表皮生长因子受体单抗疗效与皮疹相关性的系统评价

王青a - 临床荟萃, 2019 - huicui.hebmu.edu.cn
目的皮肤毒性是使用抗表皮生长因子受体(EGFR) 单抗治疗结直肠癌中早期出现和最常见的临床
现象, 然而, 皮肤毒性是否可以作为临床疗效指标目前仍然不明确. 方法计算机检索Pubmed …

Correlation between adverse events after drug treatment and the MDR1 C3435T polymorphism in advanced non-small cell lung cancer patients in an Asian …

H Luo, G Qin, C Yao - Journal of International Medical …, 2019 - journals.sagepub.com
Objective To determine the association between the multidrug resistance 1 gene (MDR1)
C3435T polymorphism and adverse drug reactions in advanced non-small cell lung cancer …

Prognostic factors in patients treated with transarterial radioembolization for unresectable and chemorefractory colorectal cancer with liver metastases

Z Jia, R Paz-Fumagalli, GT Frey, DM Sella… - Expert Review of …, 2019 - Taylor & Francis
Background: Transarterial radioembolization (TARE) is used to treat unresectable colorectal
cancer with liver metastases (CRCLM). This study aimed to assess survival after TARE and …

[HTML][HTML] Medical sciences

M Wang, OP IV, L von Kalm - Polyamine Metabolism in Disease …, 2019 - books.google.com
Increased polyamine biosynthesis activity and an active polyamine transport system are
characteristics of many cancer cell lines and polyamine depletion has been shown to be a …