Cognitive dysfunction is linked to chronic low-grade inflammatory stress that contributes to
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …

Obesity is one of the worldwide prevalent disease caused by the imbalance between food
intake and energy expenditure. Over a 100 years of research demonstrate that …

Under conditions leading to aging and metabolic syndrome, the hypothalamus atypically
undergoes proinflammatory signaling activation leading to a chronic and stable background …

Obesity is a global pandemic associated with macro-and microvascular endothelial
dysfunction. Microvascular endothelial dysfunction has recently emerged as a significant risk …

Sepsis is a deleterious immune response to infection that leads to organ failure and is the
11th most common cause of death worldwide. Despite plaguing humanity for thousands of …

Early‐life adversity (ELA) in the form of stress, inflammation, or malnutrition, can increase the
risk of developing psychopathology or cognitive problems in adulthood. The neurobiological …

Abstract Background/Objectives High-fat diet consumption is known to trigger an
inflammatory response in the hypothalamus, which has been characterized by an initial …

Abstract Background and Objectives: Elevated levels of saturated fatty acids (SFA) induce a
state of neuroinflammation in the hypothalamus. It has been suggested that microglia sense …

Abstract Background/Aims Using a reliable and valid instrument to measure appetite is
highly important in clinical practice and research. We aimed to evaluate characteristics …

Objectives Dieting often fails because weight loss triggers strong counter-regulatory
biological responses such as increased hunger and hypometabolism that are thought to be …