[HTML][HTML] Innovative approaches for cancer treatment: Current perspectives and new challenges

C Pucci, C Martinelli, G Ciofani - ecancermedicalscience, 2019 - ncbi.nlm.nih.gov
Every year, cancer is responsible for millions of deaths worldwide and, even though much
progress has been achieved in medicine, there are still many issues that must be addressed …

[HTML][HTML] Exosomal circRNAs: biogenesis, effect and application in human diseases

Y Wang, J Liu, J Ma, T Sun, Q Zhou, W Wang, G Wang… - Molecular cancer, 2019 - Springer
Exosomes have emerged as critical mediators of intercellular communication, both locally
and systemically, by regulating a diverse range of biological processes between cells …

[HTML][HTML] Design strategies and application progress of therapeutic exosomes

C Liu, C Su - Theranostics, 2019 - ncbi.nlm.nih.gov
Exosomes have great potential to be drug delivery vehicles due to their natural material
transportation properties, intrinsic long-term circulatory capability, and excellent …

Avoiding pre-isolation step in exosome analysis: direct isolation and sensitive detection of exosomes using gold-loaded nanoporous ferric oxide nanozymes

K Boriachek, MK Masud, C Palma, HP Phan… - Analytical …, 2019 - ACS Publications
Most of the current exosome-analysis strategies are time-consuming and largely dependent
on commercial extraction kit-based preisolation step, which requires extensive sample …

[HTML][HTML] The role of exosomal noncoding RNAs in cancer

Y Xie, W Dang, S Zhang, W Yue, L Yang, X Zhai… - Molecular cancer, 2019 - Springer
Extracellular vesicles (EVs) membranes enclose nanosized vesicles with a size range of 30–
150 nm and are plentiful in our body in both physiological and pathological conditions …

[HTML][HTML] Salivary biomarkers for oral squamous cell carcinoma diagnosis and follow-up: current status and perspectives

M Cristaldi, R Mauceri, O Di Fede, G Giuliana… - Frontiers in …, 2019 - frontiersin.org
Oral cancer is the sixth most common cancer type in the world, and 90% of it is represented
by oral squamous cell carcinoma (OSCC). Despite progress in preventive and therapeutic …

Mesenchymal stem cell exosomes: a two-edged sword in cancer therapy

F Vakhshiteh, F Atyabi, SN Ostad - International journal of …, 2019 - Taylor & Francis
Mesenchymal stem cells (MSCs) are multipotent stromal cells present in various adult
tissues. Several studies suggest that MSCs secrete exosomes that perform as mediators in …

Advanced liquid biopsy technologies for circulating biomarker detection

N Soda, BHA Rehm, P Sonar, NT Nguyen… - Journal of Materials …, 2019 - pubs.rsc.org
Liquid biopsy is a new diagnostic concept that provides important information for monitoring
and identifying tumor genomes in body fluid samples. Detection of tumor origin …

Emerging nanotechnologies for liquid biopsy: the detection of circulating tumor cells and extracellular vesicles

W Li, H Wang, Z Zhao, H Gao, C Liu, L Zhu… - Advanced …, 2019 - Wiley Online Library
Liquid biopsy enables noninvasive and dynamic analysis of molecular or cellular
biomarkers, and therefore holds great potential for the diagnosis, prognosis, monitoring of …

A catalytic molecule machine-driven biosensing method for amplified electrochemical detection of exosomes

Y Cao, L Li, B Han, Y Wang, Y Dai, J Zhao - Biosensors and Bioelectronics, 2019 - Elsevier
Nowadays, exosomes that carry abundant information have attracted increasing attention as
potent biomarkers of liquid biopsy and ideal candidates for early diagnosis and treatment of …