Biologics for the primary care physician: Review and treatment of psoriasis

ED Schadler, B Ortel, SL Mehlis - Disease-a-Month, 2019 - Elsevier
Psoriasis is a chronic inflammatory disease that affects approximately 7.5 million people in
the United States. The disease results in significant suffering, morbidity, and economic …

[HTML][HTML] Metabolic syndrome and skin diseases

Y Hu, Y Zhu, N Lian, M Chen, A Bartke… - Frontiers in …, 2019 - frontiersin.org
The increasing prevalence of Metabolic syndrome (MetS) is a worldwide health problem,
and the association between MetS and skin diseases has recently attracted growing …

[HTML][HTML] Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

A Budu-Aggrey, B Brumpton, J Tyrrell, S Watkins… - PLoS …, 2019 - journals.plos.org
Background Psoriasis is a common inflammatory skin disease that has been reported to be
associated with obesity. We aimed to investigate a possible causal relationship between …

Inflammasome signaling and impaired vascular health in psoriasis

MS Garshick, TJ Barrett, T Wechter… - … , and vascular biology, 2019 - Am Heart Assoc
Objective—Psoriasis is an inflammatory skin disease which heightens the risk of
cardiovascular disease. This study directly investigated vascular endothelial health and …

Metabolic syndrome and risk of incident psoriasis: prospective data from the HUNT Study, Norway

I Snekvik, TIL Nilsen, PR Romundstad… - British Journal of …, 2019 - academic.oup.com
Background Metabolic syndrome has been associated with psoriasis in cross‐sectional
studies, but data from prospective studies are sparse. Objectives To examine prospectively …

[HTML][HTML] Datura Metel L. Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis and Inhibits Inflammatory Cytokines Production through TLR7/8–MyD88–NF-κB …

BY Yang, YG Cheng, Y Liu, Y Liu, JY Tan, W Guan… - Molecules, 2019 - mdpi.com
Background: Psoriasis is a chronic, immune-mediated inflammatory skin disease, and the
inflammatory response plays an important role in its development and progression. Datura …

The relationship between smoking, psoriasis and psoriatic arthritis

E Pezzolo, L Naldi - Expert Review of Clinical Immunology, 2019 - Taylor & Francis
Introduction: Smoking is the single most important cause of preventable mortality worldwide.
Besides being associated with major cardiovascular and bronchopulmonary diseases, and …

[HTML][HTML] Phosphatidylglycerol inhibits toll-like receptor–mediated inflammation by danger-associated molecular patterns

V Choudhary, R Uaratanawong, RR Patel… - Journal of Investigative …, 2019 - Elsevier
Psoriasis is a common skin disorder characterized by hyperproliferation and aberrant
differentiation of epidermal keratinocytes and inflammation. We previously showed that …

Psoriasis and cardiovascular disease: the elusive link

AA Manolis, TA Manolis, H Melita… - International reviews of …, 2019 - Taylor & Francis
Psoriasis, an autoimmune inflammatory disease, with its most common coexisting condition,
psoriatic arthritis, seem to be more than just a local skin or joint disease, as evidence has …

[HTML][HTML] Recommendations for initiating systemic therapy in patients with psoriasis

G Martin, M Young, L Aldredge - The Journal of Clinical and …, 2019 - ncbi.nlm.nih.gov
Psoriasis is a chronic, systemic, inflammatory disease that is often associated with serious
comorbid conditions such as cardiovascular disease, obesity, and diabetes. Many patients …