Cancer overdiagnosis: a biological challenge and clinical dilemma
For cancer screening to be successful, it should primarily detect cancers with lethal potential
or their precursors early, leading to therapy that reduces mortality and morbidity. Screening …
or their precursors early, leading to therapy that reduces mortality and morbidity. Screening …
Cost-effectiveness of colorectal cancer screening strategies—a systematic review
Background & Aims Widespread screening for colorectal cancer (CRC) has reduced its
incidence and mortality. Previous studies investigated the economic effects of CRC …
incidence and mortality. Previous studies investigated the economic effects of CRC …
Cost-effectiveness and national effects of initiating colorectal cancer screening for average-risk persons at age 45 years instead of 50 years
Background & Aims The American Cancer Society has recommended initiating colorectal
cancer (CRC) screening at age 45 years instead of 50 years. We estimated the cost …
cancer (CRC) screening at age 45 years instead of 50 years. We estimated the cost …
Colorectal cancer screening with faecal testing, sigmoidoscopy or colonoscopy: a systematic review and network meta-analysis
HC Jodal, LM Helsingen, JC Anderson, L Lytvyn… - BMJ open, 2019 - bmjopen.bmj.com
Objective Evaluate effectiveness, harms and burdens of faecal blood testing, sigmoidoscopy
and colonoscopy screening for colorectal cancer over 15 years. Design We performed an …
and colonoscopy screening for colorectal cancer over 15 years. Design We performed an …
Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: long-term follow-up of the randomised US PLCO cancer screening trial
EA Miller, PF Pinsky, RE Schoen, PC Prorok… - The lancet …, 2019 - thelancet.com
Background Screening flexible sigmoidoscopy reduces incidence and mortality of colorectal
cancer. Previously reported results from the Prostate, Lung, Colorectal, and Ovarian Cancer …
cancer. Previously reported results from the Prostate, Lung, Colorectal, and Ovarian Cancer …
Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a microsimulation modelling study
Objective To estimate benefits and harms of different colorectal cancer screening strategies,
stratified by (baseline) 15-year colorectal cancer risk. Design Microsimulation modelling …
stratified by (baseline) 15-year colorectal cancer risk. Design Microsimulation modelling …
Modifiable failures in the colorectal cancer screening process and their association with risk of death
Background & Aims Colorectal cancer (CRC) deaths occur when patients do not receive
screening or have inadequate follow-up of abnormal results or when the screening test fails …
screening or have inadequate follow-up of abnormal results or when the screening test fails …
A review on curability of cancers: more efforts for novel therapeutic options are needed
Cancer remains a major cause of death globally. Given its relapsing and fatal features,
curing cancer seems to be something hardly possible for the majority of patients. In view of …
curing cancer seems to be something hardly possible for the majority of patients. In view of …
[HTML][HTML] Colorectal cancer screening from 45 years of age: thesis, antithesis and synthesis
A Mannucci, RA Zuppardo, R Rosati… - World Journal of …, 2019 - ncbi.nlm.nih.gov
Colorectal cancer incidence and mortality in patients younger than 50 years are increasing,
but screening before the age of 50 is not offered in Europe. Advanced-stage diagnosis and …
but screening before the age of 50 is not offered in Europe. Advanced-stage diagnosis and …
Plasma microRNA signature validation for early detection of colorectal cancer
M Herreros-Villanueva, S Duran-Sanchon… - Clinical and …, 2019 - journals.lww.com
OBJECTIVES: Specific microRNA (miRNA) signatures in biological fluids can facilitate
earlier detection of the tumors being then minimally invasive diagnostic biomarkers …
earlier detection of the tumors being then minimally invasive diagnostic biomarkers …