Developing and characterization of chemically modified RNA aptamers for targeting wild type and mutated c-KIT receptor tyrosine kinases

AS Shraim, A Hunaiti, A Awidi, W Alshaer… - Journal of Medicinal …, 2019 - ACS Publications
The c-KIT receptor represents an attractive target for cancer therapy. Aptamers are emerging
as a new promising class of nucleic acid therapeutics. In this study, a conventional SELEX …

Evaluation of Common Mutations in Exon 2 and 3 of the K-ras Gene in Patients with Lung Cancer

MA Saremi - Personalized Medicine Journal, 2019 - pmjournal.ir
Lung cancer is the deadliest cancer in Iran after gastric cancer. The vast majority (85%) of
cases of lung cancer are due to long-term tobacco smoking. About 10–15% of cases occur …