The metabolic signature of macrophage responses
Macrophages are a heterogeneous population of immune cells playing several and diverse
functions in homeostatic and immune responses. The broad spectrum of macrophage …
functions in homeostatic and immune responses. The broad spectrum of macrophage …
Extracellular miRNAs: from biomarkers to mediators of physiology and disease
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD
Macrophages are the gatekeepers of intestinal immune homeostasis as they discriminate
between innocuous antigens and potential pathogens to maintain oral tolerance. However …
between innocuous antigens and potential pathogens to maintain oral tolerance. However …
Macrophage polarization in physiological and pathological pregnancy
Y Yao, XH Xu, L Jin - Frontiers in immunology, 2019 - frontiersin.org
The immunology of pregnancy is complex and poorly defined. During the complex process
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …
M2b macrophage polarization and its roles in diseases
L Wang, S Zhang, H Wu, X Rong… - Journal of leukocyte …, 2019 - academic.oup.com
Macrophages play an important role in a wide variety of physiologic and pathologic
processes. Plasticity and functional polarization are hallmarks of macrophages …
processes. Plasticity and functional polarization are hallmarks of macrophages …
The effect of palmitic acid on inflammatory response in macrophages: an overview of molecular mechanisms
J Korbecki, K Bajdak-Rusinek - Inflammation Research, 2019 - Springer
Palmitic acid is a saturated fatty acid whose blood concentration is elevated in obese
patients. This causes inflammatory responses, where toll-like receptors (TLR), TLR2 and …
patients. This causes inflammatory responses, where toll-like receptors (TLR), TLR2 and …
[HTML][HTML] Exosomes from M1-polarized macrophages enhance paclitaxel antitumor activity by activating macrophages-mediated inflammation
P Wang, H Wang, Q Huang, C Peng, L Yao, H Chen… - Theranostics, 2019 - ncbi.nlm.nih.gov
Objective: Exosomes (Exos) are membrane-encased vesicles derived by nearly all cell types
for intercellular communication and regulation. They also received attention for their use as …
for intercellular communication and regulation. They also received attention for their use as …
The ERK and JNK pathways in the regulation of metabolic reprogramming
Most tumor cells reprogram their glucose metabolism as a result of mutations in oncogenes
and tumor suppressors, leading to the constitutive activation of signaling pathways involved …
and tumor suppressors, leading to the constitutive activation of signaling pathways involved …
Inflammation and inflammatory cytokine contribute to the initiation and development of ulcerative colitis and its associated cancer
D Yao, M Dong, C Dai, S Wu - Inflammatory bowel diseases, 2019 - academic.oup.com
Dysregulated inflammatory responses play a pivotal role in the initiation, development, and
progression of tumors, as demonstrated by the association between ulcerative colitis and the …
progression of tumors, as demonstrated by the association between ulcerative colitis and the …
Vital pulp therapy: histopathology and histobacteriology-based guidelines to treat teeth with deep caries and pulp exposure
D Ricucci, JF Siqueira Jr, Y Li, FR Tay - Journal of dentistry, 2019 - Elsevier
Objectives Vital pulp therapy (VPT) encompasses distinct treatment modalities for deep
caries that approximate the pulp chamber in vital teeth. Confusion exists in the literature in …
caries that approximate the pulp chamber in vital teeth. Confusion exists in the literature in …