Apparatus and method for controlling an end-effector assembly

E Butt, J Ransden, A Shvartsberg… - US Patent 10,471,607, 2019 - Google Patents
An apparatus for controlling an end-effector assembly is provided. The apparatus includes a
elongated element configured to engage the end-effector assembly and a drive assembly. A …

Selective modulation of intracellular effects of cells using pulsed electric fields

MB Sano, B Christopher, SS Verbridge… - US Patent …, 2019 - Google Patents
A system and method for selectively treating aberrant cells such as cancer cells through
administration of a train of electrical pulses is described. The pulse length and delay …

System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress

IIR Neal, RV Davalos - US Patent 10,238,447, 2019 - Google Patents
(Continued) Primary Examiner—Michael F Peffley (74) Attorney, Agent, or Firm—New River
Valley IP Law, PC; Michele L. Mayberry (57) ABSTRACT A medical system for ablating a …

High frequency electroporation for cancer therapy

B Christopher, RV Davalos, MB Sano - US Patent 10,292,755, 2019 - Google Patents
The present invention relates to the field of biomedical engineering and medical treatment of
diseases and disorders. Methods, devices, and systems for in vivo treatment of cell …

High-frequency electroporation for cancer therapy

B Christopher, RV Davalos, MB Sano - US Patent 10,448,989, 2019 - Google Patents
The present invention relates to the field of biomedical engineering and medical treatment of
diseases and disorders. Methods, devices, and systems for in vivo treatment of cell …

Electroporation with cooling to treat tissue

RV Davalos, PA Garcia, JL Robertson… - US Patent …, 2019 - Google Patents
The present invention provides methods, devices, and sys tems for in vivo treatment of cell
proliferative disorders. Included is a method of treating tissue with electrical energy, the …

Acute blood-brain barrier disruption using electrical energy based therapy

RV Davalos, JH Rossmeisl, PA Garcia - US Patent 10,245,098, 2019 - Google Patents
(57) ABSTRACT A method is provided for ablating brain tissue of a living mammal
comprising: placing first and second electrodes in a brain of the living mammal; applying a …

System and method for estimating a treatment volume for administering electrical-energy based therapies

PA Garcia, RV Davalos - US Patent 10,470,822, 2019 - Google Patents
The invention provides for a system for estimating a 3-dimensional treatment volume for a
device that applies treatment energy through a plurality of electrodes defining a treatment …

Methods for blood-brain barrier disruption using electrical energy

RV Davalos, PA Garcia, JH Rossmeisl - US Patent 10,272,178, 2019 - Google Patents
(65) Prior Publication Data US 2017/0189579 A1 Jul. 6, 2017 Related US Application Data
(60) Continuation-in-part of application No. 12/432, 295, filed on Apr. 29, 2009, now Pat. No …

Irreversible electroporation to create tissue scaffolds

RV Davalos - US Patent 10,286,108, 2019 - Google Patents
2018-12-21 Assigned to VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY
reassignment VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY …