Pulmonary hypertension in chronic lung disease and hypoxia

SD Nathan, JA Barbera, SP Gaine… - European …, 2019 - Eur Respiratory Soc
Pulmonary hypertension (PH) frequently complicates the course of patients with various
forms of chronic lung disease (CLD). CLD-associated PH (CLD-PH) is invariably associated …

Phosphodiesterase 5 inhibitors for pulmonary hypertension

H Barnes, Z Brown, A Burns… - Cochrane Database of …, 2019 - cochranelibrary.com
Background Pulmonary hypertension (PH) comprises a group of complex and heterogenous
conditions, characterised by elevated pulmonary artery pressure, and which left untreated …

[HTML][HTML] Circular RNA hsa_circ_0016070 is associated with pulmonary arterial hypertension by promoting PASMC proliferation

S Zhou, H Jiang, M Li, P Wu, L Sun, Y Liu, K Zhu… - … Therapy-Nucleic Acids, 2019 - cell.com
Noncoding RNAs play an important role in the pathogenesis of pulmonary arterial
hypertension (PAH). In this study, we investigated the roles of hsa_circ_0016070, miR-942 …

Nintedanib and sildenafil in patients with idiopathic pulmonary fibrosis and right heart dysfunction. A prespecified subgroup analysis of a double-blind randomized …

J Behr, M Kolb, JW Song, F Luppi… - American Journal of …, 2019 - atsjournals.org
Rationale: In the INSTAGE trial in patients with idiopathic pulmonary fibrosis (IPF) and
severely impaired gas exchange, nintedanib plus sildenafil was associated with numerical …

Pulmonary hypertension due to interstitial lung disease

CS King, SD Nathan - Current Opinion in Pulmonary Medicine, 2019 - journals.lww.com
The development of pulmonary hypertension is associated with increased exertional oxygen
requirements, worsened functional capacity and attenuated life expectancy. It is hoped that …

[HTML][HTML] Pulmonary hypertension in intensive care units: an updated review

A Nowroozpoor, M Malekmohammad, SR Seyyedi… - Tanaffos, 2019 - ncbi.nlm.nih.gov
Pulmonary hypertension (PH) is a condition associated with high morbidity and mortality.
Patients with PH who require critical care usually have severe right ventricular (RV) …

Hypoxic pulmonary vasoconstriction and the diffusing capacity in pulmonary hypertension secondary to idiopathic pulmonary fibrosis

S Sakao, N Tanabe, K Tatsumi - Journal of the American Heart …, 2019 - Am Heart Assoc
Idiopathic pulmonary fibrosis (IPF) has a worse prognosis when complicated with pulmonary
hypertension (PH). There are% 3 million patients with IPF around the world, 1, 2 and the …

Improvement of pulmonary arterial hypertension, inflammatory response, and epithelium injury by dual activation of cAMP/cGMP pathway in a rat model of …

Y Muraki, T Naito, K Tohyama, S Shibata… - Bioscience …, 2019 - academic.oup.com
Pulmonary hypertension (PH) is a life-threatening lung disease. PH with concomitant lung
diseases, eg, idiopathic pulmonary fibrosis, is associated with poor prognosis. Development …

[PDF][PDF] Toxic effects of sexual drug overdose: sildenafil (Viagra)

RK Verma, MS Sankhla, R Kumar - ARC Journal of Forensic …, 2019 - researchgate.net
In today's world main problem adolescence consumption of drugs are increasing day by
day. Sildenafil is the sexual drug. Sildenafil is the drug which to increase sexual power and …

p38 mitogen activated protein kinase mediates cardiac Na+/H+ exchanger inhibition induced by Sildenafil

RG Díaz, DS Escudero, MS Brea, PE Morgan… - European journal of …, 2019 - Elsevier
Since the original description as potent antianginal compounds, phosphodiesterase 5A
inhibitors have continuously increased their possible therapeutic applications. In the heart …