Dietary antioxidants as a source of hydrogen peroxide

M Grzesik, G Bartosz, I Stefaniuk, M Pichla… - Food chemistry, 2019 - Elsevier
Studies of 54 antioxidants revealed that 27 of them, mainly polyphenols, generated
hydrogen peroxide (H 2 O 2) when added to Dulbecco's modified Eagle's medium (DMEM) …

Mechanisms of color formation in drug substance and mitigation strategies for the manufacture and storage of therapeutic proteins produced using mammalian cell …

C Du, J Xu, H Song, L Tao, A Lewandowski… - Process …, 2019 - Elsevier
Drug substance (DS) appearance is an important quality attribute that is tested before
product release. Color variation in DS batches or color change during storage can be …

Polymersome nanoreactors with tumor pH-triggered selective membrane permeability for prodrug delivery, activation, and combined oxidation-chemotherapy

JF Mukerabigwi, W Yin, Z Zha, W Ke, Y Wang… - Journal of Controlled …, 2019 - Elsevier
Therapeutic nanoreactors are currently emerging as promising nanoplatforms to in situ
transform inert prodrugs into active drugs. Nevertheless, it is still challenging to engineer a …

[HTML][HTML] Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants

S Salati, E Genovese, C Carretta, R Zini, N Bartalucci… - Scientific reports, 2019 - nature.com
Somatic mutations of calreticulin (CALR) have been described in approximately 60–80% of
JAK2 and MPL unmutated Essential Thrombocythemia and Primary Myelofibrosis patients …

Caution for the routine use of phenol red–it is more than just a pH indicator

A Morgan, D Babu, B Reiz, R Whittal, LYK Suh… - Chemico-biological …, 2019 - Elsevier
Phenol red (PR) is the standard pH indicator in various cell and tissue culture media, as it
provides a quick check for the health of the culture. PR has also been used in multiple …

Interactive effects of As, Cd and Zn on their uptake and oxidative stress in As-hyperaccumulator Pteris vittata

R Abid, M Manzoor, LM De Oliveira, E da Silva… - Environmental …, 2019 - Elsevier
The effects of arsenic (As), cadmium (Cd) and zinc (Zn) on each other's uptake and oxidative
stress in As-hyperaccumulator Pteris vittata were investigated. P. vittata plants were exposed …

[HTML][HTML] Antimicrobial Effect of Visible Light—Photoinactivation of Legionella rubrilucens by Irradiation at 450, 470, and 620 nm

J Schmid, K Hoenes, P Vatter, M Hessling - Antibiotics, 2019 - mdpi.com
Despite the high number of legionella infections, there are currently no convincing
preventive measures. Photoinactivation with visible light is a promising new approach and …

Between life and death: reducing phototoxicity in super-resolution microscopy

KL Tosheva, Y Yuan, PM Pereira, S Culley… - 2019 - preprints.org
Abstract Super-Resolution Microscopy enables non-invasive, molecule-specific imaging of
the internal structure and dynamics of cells with sub-diffraction limit spatial resolution. One of …

Combination of nutrients in a mammalian cell culture medium kills cryptococci

DL Granger, DM Call - Medical Mycology, 2019 - academic.oup.com
We found that a large inoculum of Cryptococcus gattii cells, when plated on Dulbecco's
modified eagle's medium (DMEM) incorporated into agar, died within a few hours provided …

[图书][B] Incident light modulation by means of power variations and light pulsing reduces photo induced toxicity and bleaching

F Mubaid - 2019 - search.proquest.com
The use of fluorescence in microscopy has introduced unprecedented specificity and
contrast, paving the way for highly specialized techniques and applications such as …