Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

Current management of aortic aneurysms relies exclusively on prophylactic operative repair
of larger aneurysms. Great potential exists for successful medical therapy that halts or …

Although angiotensin II (AngII) is known to cause renal injury and fibrosis, the underlying
mechanisms remain poorly characterized. Here we show that hypertensive nephropathy …

Abdominal aortic aneurysm (AAA) is a local dilatation of the abdominal aortic vessel wall
and is among the most challenging cardiovascular diseases as without urgent surgical …

Background Breast cancer is the second common malignant cancer among females
worldwide. Accumulating studies have indicated that deregulation of miRNA expression in …

This study was designed to determine the effects of the long non-coding RNA (lncRNA)
plasmacytoma variant translocation 1 (PVT1) on vascular smooth muscle cell (VSMC) …

Objectives Fluoroquinolone (FQ) antibiotics are associated with adverse aortic clinical
events. We assessed human aortic myofibroblast-mediated extracellular matrix (ECM) …

Cardiovascular diseases encompassing atherosclerosis, aortic aneurysms, restenosis, and
pulmonary arterial hypertension, remain the leading cause of morbidity and mortality …

Cardiovascular disease remains the number one cause of death and disability worldwide
despite significant improvements in diagnosis, prevention, and early intervention efforts …

miR-29a-3p has been shown to be associated with cardiovascular diseases; however, the
effect of miR-29a-3p on endothelial dysfunction is unclear. This study aimed to reveal the …