Abstract CD133 (prominin-1), a pentaspan membrane glycoprotein, is one of the most well-
characterized biomarkers used for the isolation of cancer stem cells (CSCs). The presence …

In recent years, the term “extracellular vesicle”(EV) has been used to define different types of
vesicles released by various cells. It includes plasma membrane‐derived vesicles …

Glioblastoma (GB) is the more frequent and malignant brain tumour. In spite of all efforts, the
median overall survival of GB patients remains approximately 15 months under therapy. The …

Background: Pancreatic ductal adenocarcinoma (PDAC) requires multimodal therapeutic
approaches and disease monitoring for effective treatment. Liquid biopsy biomarkers …

Results A total of 2950 proteins were isolated from microvesicles and exosomes, including
1579 (54%) identified in all samples but only 178 (6%) and 88 (3%) specific for medullary …

Proper temporal and spatial activation of stem cells relies on highly coordinated cell
signaling. The primary cilium is the sensory organelle that is responsible for transmitting …

Prominin‐1 is a cell surface biomarker that allows the identification of stem and cancer stem
cells from different organs. It is also expressed in several differentiated epithelial and non …

CD133 is a transmembranous protein that mainly localises to the plasma membrane in
haematopoietic and neural stem cells as well as cancer stem cells. Although CD133 also …

Purpose To describe the genetic and phenotypic characteristics of a cohort of patients with
PROM1 variants. Design Case-case study. Methods We screened a cohort of 2216 families …

Centrins (CETN1–4) are ubiquitous and conserved EF-hand–family Ca 2+-binding proteins
associated with the centrosome, basal body, and transition zone. Deletion of CETN1 or …