Paediatric pulmonary arterial hypertension (PAH) shares common features of adult disease,
but is associated with several additional disorders and challenges that require unique …

Successful resuscitation from cardiac arrest results in a post–cardiac arrest syndrome, which
can evolve in the days to weeks after return of sustained circulation. The components of post …

Pulmonary hypertension (PH) is highly heterogeneous and despite treatment advances it
remains a life-shortening condition. There have been significant advances in imaging …

Rationale: Congenital diaphragmatic hernia (CDH) is an anomaly with a high morbidity and
mortality. Cardiac dysfunction may be an important and underrecognized contributor to CDH …

Background: Home oxygen therapy is often required in children with chronic respiratory
conditions. This document provides an evidence-based clinical practice guideline on the …

Background Group 1 pulmonary arterial hypertension (PAH) is a rare disease with high
mortality despite recent therapeutic advances. Pathogenic remodeling of pulmonary …

Rare variants in the T-box transcription factor 4 gene (TBX4) have recently been recognised
as an emerging cause of paediatric pulmonary hypertension (PH). Their pathophysiology …

In 1967, Northway and colleagues 1 described bronchopulmonary dysplasia (BPD) as a
lung condition of prematurity that began with diffuse parenchymal lung disease and a …

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling
resulting in right ventricular (RV) dysfunction and ultimately RV failure. Mechanical stimuli …

Effective ventilation of the lungs is essential in mediating pulmonary vasodilation at birth to
allow effective gas exchange and an increase in systemic oxygenation. Unsuccessful …