[HTML][HTML] Multifunctional cationic nanosystems for nucleic acid therapy of thoracic aortic dissection

C Xu, Y Zhang, K Xu, JJ Nie, B Yu, S Li… - Nature …, 2019 - nature.com
Thoracic aortic dissection (TAD) is an aggressive vascular disease that requires early
diagnosis and effective treatment. However, due to the particular vascular structure and …

Mechanical characterisation of human ascending aorta dissection

V Deplano, M Boufi, V Gariboldi, AD Loundou… - Journal of …, 2019 - Elsevier
Mechanical characteristics of both the healthy ascending aorta and acute type A aortic
dissection were investigated using in vitro biaxial tensile tests, in vivo measurements via …

[HTML][HTML] Differential outcomes of open and clamp-on distal anastomosis techniques in acute type A aortic dissection

A Geirsson, K Shioda, C Olsson, A Ahlsson… - The Journal of thoracic …, 2019 - Elsevier
Objectives Open-distal anastomosis is the preferred technique over clamp-on technique for
surgical repair of acute type A aortic dissection (ATAAD). The aim of this study was to define …

[HTML][HTML] Acute aortic dissections with entry tear in the arch: A report from the International Registry of Acute Aortic Dissection

S Trimarchi, HWL de Beaufort, JL Tolenaar… - The Journal of thoracic …, 2019 - Elsevier
Objective To analyze presentation, management, and outcomes of acute aortic dissections
with proximal entry tear in the arch. Methods Patients enrolled in the International Registry of …

[HTML][HTML] Effects of sex on early outcome following repair of acute type A aortic dissection: results from the Nordic Consortium for Acute Type A Aortic Dissection …

RA Chemtob, V Hjortdal, A Ahlsson, J Gunn… - Aorta, 2019 - thieme-connect.com
Background Female sex is known to have increased perioperative mortality in cardiac
surgery. Studies reporting effects of sex on outcome following surgical repair for acute Type …

[HTML][HTML] Extracellular matrix in ascending aortic aneurysms and dissections–what we learn from decellularization and scanning electron microscopy

T Mimler, C Nebert, E Eichmair, B Winter, T Aschacher… - PloS one, 2019 - journals.plos.org
Pathological impairment of elastic fiber and other extracellular matrix (ECM) components are
described for the aortic media of ascending thoracic aortic aneurysms (aTAA) but the exact …

Stable population-based incidence of acute type A and B aortic dissection

S Acosta, A Gottsäter - Scandinavian Cardiovascular Journal, 2019 - Taylor & Francis
Background. Aortic dissection (AD) and abdominal aortic aneurysm (AAA) share the same
risk factors. Whereas the incidence of AAA is falling, it is unclear whether population-based …

Upregulation of miR‐146a‐5p is associated with increased proliferation and migration of vascular smooth muscle cells in aortic dissection

L Xue, S Luo, H Ding, Y Liu, W Huang… - Journal of Clinical …, 2019 - Wiley Online Library
Background This study aimed to investigate whether miR‐146a‐5p was involved in the
pathogenesis of thoracic aortic dissection (AD) via regulating the biological function of …

[HTML][HTML] HSP90 inhibitor 17-DMAG effectively alleviated the progress of thoracic aortic dissection by suppressing smooth muscle cell phenotypic switch

Z Zhao, Y Wang, S Li, S Liu, Y Liu, Y Yu… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Thoracic aortic dissection (TAD) is a highly lethal vascular disease characterized by medial
degeneration. Heat shock protein 90 (HSP90) had been proved as a potential target for a …

[HTML][HTML] Lipidomic signatures of aortic media from patients with atherosclerotic and nonatherosclerotic aneurysms

K Saito, H Yagi, K Maekawa, M Nishigori… - Scientific Reports, 2019 - nature.com
Aortic aneurysms are associated with fatal aortic rupture. Current therapeutic approaches
are limited to implantation of aortic prostheses and stent-grafts; no effective drugs are …