Aortic dissections and aortic aneurysms are fatal events characterized by structural changes
to the aortic wall. The maximum diameter criterion, typically used for aneurysm rupture risk …

Arterial stiffness is an age-related disorder. In the medial layer of arteries, mechanical
fracture due to fatigue failure for the pulsatile wall strain causes medial degeneration …

Current clinical practice for aneurysmatic interventions is often based on the maximum
diameter of the vessel and/or on the growth rate, although rupture can occur at any diameter …

The stiffness of arterial wall in response to cardiovascular diseases has been associated
with the changes in extracellular matrix (ECM) proteins, ie., collagen and elastin. Vascular …

Abstract Background High serum phosphate (Pi) levels strongly associate with
cardiovascular morbidity and mortality in chronic kidney disease (CKD) patients with …

Aortic dissections associate with medial degeneration, thus suggesting a need to
understand better the biophysical interactions between the cells and matrix that constitute …

Pathological impairment of elastic fiber and other extracellular matrix (ECM) components are
described for the aortic media of ascending thoracic aortic aneurysms (aTAA) but the exact …

Multiphoton‐induced second‐harmonic generation and two‐photon excitation enable
imaging of collagen and elastin fibers at micron‐level resolution to depths of hundreds of …

Tissue-engineered vascular grafts (TEVGs) have shown significant promise; however,
progression toward clinical application has been limited by the use of slow degrading …

Scaffold designs in combination with drug, growth factor and other bioactive chemicals
account for lasting progress of vascular tissue engineering in the past decades. It is a great …