Non-resolving inflammation is the main mechanism of morbidity and mortality among
patients suffering from cystic fibrosis (CF), the most common life-threatening human genetic …

Chronic rhinosinusitis (CRS) is nearly ubiquitous in patients with cystic fibrosis (CF). CF
CRS is a challenging entity to define, diagnose, and treat, as patients often have severe …

Aims Pseudomonas aeruginosa is one of the leading causes of opportunistic and hospital-
acquired infections worldwide, which is frequently linked with clinical treatment difficulties …

Mesenchymal stem cells (MSCs) are multipotent non-hematopoietic stem cells residing in
many tissues, including the lung. MSCs have long been regarded as a promising tool for cell …

Bone repair after trauma or surgical intervention involves a tightly regulated cascade of
events that starts with hemostasis and an inflammatory response, which are critical for …

The study was designed to investigate the effect of Nimesulide (NIM) on acute lung injury
(ALI) in mice with severe acute pancreatitis (SAP). In our study, caerulein and LPS were …

Epilepsy is a chronic neurological disease. Astrogliosis is an important pathological change
in epileptic lesions. Studies have reported that ibuprofen can affect autophagy and/or inhibit …

Cystic fibrosis (CF) is a multisystem disorder caused by pathogenic mutations of the CFTR
gene (CF transmembrane conductance regulator). Pulmonary disease remains the leading …

Cystic fibrosis is a genetic disease typically characterized by progressive lung damage and
premature mortality. Pulmonary exacerbations, or flare-ups of the lung disease, often require …

Aim: The objective of this study was to develop suitable lipid nanocarriers for topical delivery
of Piroxicam, known for its anti-inflammatory and anti-arthritic properties and to increase its …