The chemistry of boronic acids in nanomaterials for drug delivery

A Stubelius, S Lee, A Almutairi - Accounts of chemical research, 2019 - ACS Publications
Conspectus Interest in increasing drug delivery efficiency has risen over the past decade
both as a means to improve efficacy of already clinically available drugs and due to the …

Trends in polymeric shape memory hydrogels and hydrogel actuators

J Shang, X Le, J Zhang, T Chen, P Theato - Polymer Chemistry, 2019 - pubs.rsc.org
Recently,“smart” hydrogels with either shape memory behavior or reversible actuation have
received particular attention and have been further developed into sensors, actuators, or …

[HTML][HTML] Design of moldable hydrogels for biomedical applications using dynamic covalent boronic esters

B Marco-Dufort, MW Tibbitt - Materials Today Chemistry, 2019 - Elsevier
Traditional polymeric materials based on thermosets or thermoplastics are applied broadly
as biomedical materials. While attractive for a range of applications, thermosets and …

Environment sensitive hydrogels for drug delivery applications

D Qureshi, SK Nayak, S Maji, A Anis, D Kim… - European Polymer …, 2019 - Elsevier
Over the last few decades, hydrogels have attracted the considerable interest of researchers
for crafting potential controlled drug delivery systems. It may be attributed to their high water …

Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs

J Wang, J Yu, Y Zhang, X Zhang, AR Kahkoska… - Science …, 2019 - science.org
Glucose-responsive insulin delivery systems with robust responsiveness that has been
validated in animal models, especially in large animal models, remain elusive. Here, we …

Hydrogels based drug delivery synthesis, characterization and administration

A Onaciu, RA Munteanu, AI Moldovan, CS Moldovan… - Pharmaceutics, 2019 - mdpi.com
Hydrogels represent 3D polymeric networks specially designed for various medical
applications. Due to their porous structure, they are able to swollen and to entrap large …

Modular fabrication of intelligent material-tissue interfaces for bioinspired and biomimetic devices

JR Clegg, AM Wagner, SR Shin, S Hassan… - Progress in materials …, 2019 - Elsevier
One of the goals of biomaterials science is to reverse engineer aspects of human and non-
human physiology. Similar to the body's regulatory mechanisms, such devices must …

Injectable self-healing hydrogels based on boronate ester formation between hyaluronic acid partners modified with benzoxaborin derivatives and saccharides

T Figueiredo, J Jing, I Jeacomine, J Olsson… - …, 2019 - ACS Publications
We demonstrate here, for the first time, formation of injectable dynamic covalent hydrogels at
physiological pH using benzoxaborin-saccharide complexation as a reversible cross-linking …

Strong dual-crosslinked hydrogels for ultrasound-triggered drug delivery

W Sun, H Jiang, X Wu, Z Xu, C Yao, J Wang, M Qin… - Nano Research, 2019 - Springer
Hydrogels that can respond to dynamic forces either from endogenous biological activities
or from external mechanical stimuli show great promise as novel drug delivery systems …

Biologically inspired and chemically derived methods for glucose‐responsive insulin therapy

MA VandenBerg, MJ Webber - Advanced Healthcare Materials, 2019 - Wiley Online Library
The controlled delivery of therapeutics in a manner responsive to physiological indicators
has promise in realizing new therapeutic approaches to combat disease. This approach is …