Role of intestinal microbiota in the bioavailability and physiological functions of dietary polyphenols

K Kawabata, Y Yoshioka, J Terao - Molecules, 2019 - mdpi.com
Polyphenols are categorized as plant secondary metabolites, and they have attracted much
attention in relation to human health and the prevention of chronic diseases. In recent years …

Beneficial effects of dietary polyphenols on high-fat diet-induced obesity linking with modulation of gut microbiota

J Liu, Z He, N Ma, ZY Chen - Journal of agricultural and food …, 2019 - ACS Publications
Obesity is caused by an imbalance of energy intake and expenditure. It is characterized by a
higher accumulation of body fat with a chronic low-grade inflammation. Many reports have …

Combinatorial epigenetics impact of polyphenols and phytochemicals in cancer prevention and therapy

I Arora, M Sharma, TO Tollefsbol - International journal of molecular …, 2019 - mdpi.com
Polyphenols are potent micronutrients that can be found in large quantities in various food
sources and spices. These compounds, also known as phenolics due to their phenolic …

Synergistic anti-inflammatory effects and mechanisms of combined phytochemicals

L Zhang, C Virgous, H Si - The Journal of nutritional biochemistry, 2019 - Elsevier
The anti-inflammatory effects of phytochemicals, bioactive components from plants having
health benefits, have been heavily investigated in the last several decades. However, the …

[PDF][PDF] Phenolic compounds in agri-food by-products, their bioavailability and health effects

F Shahidi, V Varatharajan, WY Oh, H Peng - Food Bioact, 2019 - researchgate.net
Phenolic compounds constitute a large and diverse group of secondary metabolites derived
from phenylalanine and tyrosine and are widely distributed throughout the plant kingdom …

Antioxidant categories and mode of action

MA Aziz, AS Diab, AA Mohammed - Antioxidants, 2019 - books.google.com
Oxidative stress has received a considerable scientific attention as a mediator in the etiology
of many human diseases. Oxidative stress is the result of an imbalance between free …

Anthocyanins improve hippocampus-dependent memory function and prevent neurodegeneration via JNK/Akt/GSK3β signaling in LPS-treated adult mice

MS Khan, T Ali, MW Kim, MH Jo, JI Chung… - Molecular …, 2019 - Springer
Microglia plays a critical role in the brain and protects neuronal cells from toxins. However,
over-activation of microglia leads to deleterious effects. Lipopolysaccharide (LPS) has been …

Low-molecular weight metabolites from polyphenols as effectors for attenuating neuroinflammation

D Carregosa, R Carecho, I Figueira… - Journal of agricultural …, 2019 - ACS Publications
Age-associated pathophysiological changes such as neurodegenerative diseases are
multifactorial conditions with increasing incidence and no existing cure. The possibility of …

Targeting carbohydrates and polyphenols for a healthy microbiome and healthy weight

M Van Hul, PD Cani - Current nutrition reports, 2019 - Springer
Abstract Purpose of Review In this review, we focus on microbiota modulation using non-
digestible carbohydrate and polyphenols (ie, prebiotics) that have the potential to modulate …

Red wine extract preserves tight junctions in intestinal epithelial cells under inflammatory conditions: Implications for intestinal inflammation

C Nunes, V Freitas, L Almeida, J Laranjinha - Food & function, 2019 - pubs.rsc.org
The altered expression and subcellular distribution of tight junction (TJ) proteins, leading to
a dysfunctional intestinal barrier, is a key mechanistic feature of inflammatory bowel disease …