Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases

MJ Betts, E Kirilina, MCG Otaduy, D Ivanov… - Brain, 2019 - academic.oup.com
Pathological alterations to the locus coeruleus, the major source of noradrenaline in the
brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI …

[HTML][HTML] The role of dopamine in the brain-lessons learned from Parkinson's disease

D Meder, DM Herz, JB Rowe, S Lehéricy, HR Siebner - Neuroimage, 2019 - Elsevier
Parkinson's disease causes a characteristic combination of motor symptoms due to
progressive neurodegeneration of dopaminergic neurons in the substantia nigra pars …

[HTML][HTML] Functional imaging correlates of akinesia in Parkinson's disease: Still open issues

C Spay, G Meyer, ML Welter, B Lau, P Boulinguez… - NeuroImage: Clinical, 2019 - Elsevier
Akinesia is a major manifestation of Parkinson's disease (PD) related to difficulties or failures
of willed movement to occur. Akinesia is still poorly understood and is not fully alleviated by …

Modulating functional connectivity with non-invasive brain stimulation for the investigation and alleviation of age-associated declines in response inhibition: A …

J Tan, KK Iyer, AD Tang, A Jamil, RN Martins… - NeuroImage, 2019 - Elsevier
Response inhibition, the ability to withhold a dominant and prepotent response following a
change in circumstance or sensory stimuli, declines with advancing age. While non-invasive …

[HTML][HTML] Aftereffect and reproducibility of three excitatory repetitive tms protocols for a response inhibition task

GJ Ji, JJ Wei, T Liu, D Li, C Zhu, F Yu, Y Tian… - Frontiers in …, 2019 - frontiersin.org
A number of repetitive transcranial magnetic stimulation (rTMS) protocols have been
developed for modulating brain function non-invasively. To identify the most powerful one …

Functional imaging studies of impulse control disorders in Parkinson's disease need a stronger neurocognitive footing

GM Meyer, C Spay, C Laurencin, B Ballanger… - Neuroscience & …, 2019 - Elsevier
Impulse control disorders (ICDs) in Parkinson's disease (PD) are associated with
dopaminergic dysfunction and treatment, but have no satisfactory therapeutic solution. While …

Atomoxetine and citalopram alter brain network organization in Parkinson's disease

RJ Borchert, T Rittman, CL Rae… - Brain …, 2019 - academic.oup.com
Parkinson's disease has multiple detrimental effects on motor and cognitive systems in the
brain. In contrast to motor deficits, cognitive impairments in Parkinson's disease are usually …

Neuropsychiatric aspects of Parkinson disease psychopharmacology: Insights from circuit dynamics

A Butala, M Shepard, G Pontone - Handbook of Clinical Neurology, 2019 - Elsevier
Parkinson disease (PD) is a neurodegenerative disorder with a complex pathophysiology
characterized by the progressive loss of dopaminergic neurons within the substantia nigra …

[HTML][HTML] Neurobiology and clinical features of impulse control failure in Parkinson's disease

M Béreau, P Krack, N Brüggemann… - Neurological research and …, 2019 - Springer
Impulse control disorders (ICDs) and other impulsive-compulsive related behaviours are
frequent and still under recognized non-motor complications of Parkinson's disease (PD) …

Resting state oscillations suggest a motor component of Parkinson's Impulse Control Disorders

C Spay, G Meyer, G Lio, G Pezzoli, B Ballanger… - Clinical …, 2019 - Elsevier
Abstract Objectives Impulse control disorders (ICDs) in Parkinson's disease (PD) have been
associated with cognitive impulsivity and dopaminergic dysfunction and treatment. The …