Multiphoton microscopy in surgical oncology-a systematic review and guide for clinical translatability

TT König, J Goedeke, OJ Muensterer - Surgical Oncology, 2019 - Elsevier
Background Multiphoton microscopy (MPM) facilitates three-dimensional, high-resolution
functional imaging of unlabeled tissues in vivo and ex vivo. This systematic review discusses …

[HTML][HTML] Optical signatures derived from deep UV to NIR excitation discriminates healthy samples from low and high grades glioma

H Mehidine, A Chalumeau, F Poulon, F Jamme… - Scientific Reports, 2019 - nature.com
Among all the tumors of the central nervous system (CNS), glioma are the most deadly and
the most malignant. Surgical resection is the standard therapeutic method to treat this type of …

Maximizing the extent of resection in high-grade glioma

G Grasso, F Torregrossa, L Leone - World Neurosurgery, 2019 - iris.unipa.it
High-grade gliomas (HGGs) are devastating tumors associated with one of the worst
prognoses in oncology. Glioblastoma multiforme (GBM) is the most frequently reported …

Quantitative assessment of microenvironment characteristics and metabolic activity in glioma via multiphoton microscopy

N Fang, Z Wu, X Wang, Y Lin, L Li… - Journal of …, 2019 - Wiley Online Library
Tumor microenvironment and metabolic activity in gliomas are the important biomarkers to
evaluate the progression of gliomas. Many evidences have suggested that the targeting of …

Comparison of optically‐derived biomarkers in healthy and brain tumor tissue under one‐and two‐photon excitation

M Sibai, H Mehidine, EK Moawad… - Journal of …, 2019 - Wiley Online Library
The surgical outcome of brain tumor resection and needle biopsy is significantly correlated
to the patient's prognosis. Brain tumor surgery is limited to resecting the solid portion of the …