Monocytes are innate immune cells of the mononuclear phagocyte system that have
emerged as important regulators of cancer development and progression. Our …

Monocytes are innate blood cells that maintain vascular homeostasis and are early
responders to pathogens in acute infections. There are three well-characterized classes of …

Tumor-infiltrating myeloid cells (TIMs) comprise monocytes, macrophages, dendritic cells,
and neutrophils, and have emerged as key regulators of cancer growth. These cells can …

Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to
their unique ability to initiate T cell responses and direct their differentiation into effector …

While the roles of parenchymal microglia in brain homeostasis and disease are fairly clear,
other brain-resident myeloid cells remain less well understood. By dissecting border regions …

The mononuclear phagocyte system (MPS) is defined as a cell lineage in which committed
marrow progenitors give rise to blood monocytes and tissue macrophages. Here, we discuss …

Classical and non-classical monocytes, and the macrophages and monocyte-derived
dendritic cells they produce, play key roles in host defense against pathogens, immune …

Resident tissue macrophages (RTM) can fulfill various tasks during development,
homeostasis, inflammation and repair. In the lung, non-alveolar RTM, called interstitial …

Mesenchymal stromal/stem cell (MSC) therapy has shown promise in experimental models
of idiopathic pulmonary fibrosis (IPF). The aim of this study was to test the therapeutic effects …

Myeloid cells are a major cellular compartment of the immune system comprising
monocytes, dendritic cells, tissue macrophages, and granulocytes. Models of cellular …