Life expectancy in the West is the highest it has ever been, due to the introduction of better
hygiene practices and sophisticated medical interventions for cancer, autoimmunity and …

Fungal infections of the central nervous system are responsible for significant morbidity and
mortality. Cryptococcus neoformans (Cn) is the primary cause of fungal meningitis. Infection …

These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …

Fungal dissemination into the bloodstream is a critical step leading to invasive fungal
infections. Here, using intravital imaging, we show that Kupffer cells (KCs) in the liver have a …

The majority of invasive human fungal pathogens gain access to their human hosts via the
inhalation of spores from the environment into the lung, but relatively little is known about …

Cryptococcus neoformans is an encapsulated yeast responsible for approximately a quarter
of a million deaths worldwide annually despite therapy, and upwards of 11% of HIV/AIDS …

Cryptococcal meningitis is an uncommon and severe infection that tends to affect
immunocompromised hosts worldwide and in the United States. Annually it is estimated that …

Cryptococcus neoformans is a ubiquitous environmental yeast and a leading cause of
invasive fungal infection in humans. The most recent estimate of global disease burden …

Background: Neurological disorders in HIV infection are a common cause of morbidity and
mortality. The aim of this paper is to provide a narrative overview of up to date information …

Background For definitive diagnosis of cryptococcal meningitis, Cryptococcus neoformans
and/or C. gattii must be identified within cerebral spinal fluid from the patients. The traditional …