Background Methamphetamine (METH) use disorder is prevalent worldwide. There are
reports of sex differences in quantities of drug used and relapses to drug use among …

Understanding the neurobiological processes that incite drug craving and drive relapse has
the potential to help target efforts to treat addiction. The NAc serves as a critical substrate for …

Addiction to the psychostimulant Methamphetamine (METH) is characterised by high rates of
relapse. Currently there are no approved effective pharmacotherapies for METH …

Background: Individuals with post-traumatic stress disorder (PTSD) have a heightened
sensitivity to subsequent stressors, addictive drugs, and symptom recurrence, a form of …

Recently, the insular cortex (IC) was identified as part of the neuronal circuit responsible for
the reward expectations in cue-triggered behaviours. Moreover, there are evidences that …

Small fluctuations in striatal glutamate and dopamine are required to establish goal‐directed
behaviors and motor learning, while large changes appear to underlie many …

Cocaine-induced plasticity persists during abstinence and is thought to underlie cue-evoked
craving. Reversing this plasticity could provide an opportunity for therapeutic intervention …

Drug-specific reward and associated effects on neural signaling are often studied between
subjects, where one group self-administers drug and a separate group self-administers a …

L'addiction aux drogues est une maladie comportementale récidivante caractérisée par une
recherche et une prise compulsive de drogues, une perte de contrôle sur la prise malgré les …