Primary graft dysfunction (PGD) remains the leading cause of early mortality post-heart
transplantation. Despite improvements in mechanical circulatory support and critical care …

The thyroid gland produces hormones that primarily regulate cellular metabolism, have wide-
ranging pleiotropic effects, and are essential for life. During critical illness, the most active …

Rationale Brain‐dead (BD) organ donors frequently exhibit hemodynamic instability and/or
reversible cardiac dysfunction. Retrospective studies have suggested that thyroid hormone …

Objective The effect of thyroid dysfunction on adverse outcomes has been studied in many
different patient populations. The objective of this study was to investigate the effect of …

Organs transplanted from deceased donors provide effective life-saving and lifeenhancing
treatment for many individuals with end-stage organ failure. Most of the donors have been …

Management of the pediatric organ donor necessitates understanding the physiologic
changes that occur preceding and after death determination. Recognizing these changes …

El trasplante de órganos es un procedimiento vital para el reemplazo de órganos en falla
irreversible. En Chile, el promedio de donantes es muy inferior a países en que el proceso …

Résumé La réanimation d'un patient en état de mort encéphalique (EME) a pour finalité la
réalisation d'un prélèvement d'organes et de tissus. La qualité de la réanimation influence …

Deceased donation of kidneys for transplantation may occur through either brain death (BD)
or donation after circulatory death (DCD) pathways with similar long-term benefit. Absolute …

This issue of Critical Care Clinics, Guest Edited by Dr. Rinaldo Bellomo, focuses on Modern
Critical Care Endocrinology. Article topics include: Diabetes insipidus and SIADH in the ICU; …